9 Results for "

Cyto c

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Cyto c" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-103349
CAS No.: 10129-56-3
Purity:  99.68%
Target:  

Caspase Apoptosis

Research Areas:  

Cancer

PETCM is an activator of caspase-3 and acts as an cytochrome c (cyto c)-dependent manner. PETCM promotes Apaf-1 oligomerization and induces cell apoptosis in HeLa cells .
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Cat. No.: HY-N6017
CAS No.: 19906-72-0
Bakkenolide A is an anticancer agent. Bakkenolide A reduces the viability of leukemia cells, inhibits cell colony formation and invasion, and downregulates the expression of HDAC3 in cells. Bakkenolide A downregulates the expression of pro-inflammatory cytokines including TNF-α, interleukins such as IL-1β, TGF-β1 and IFN-γ, as well as the expression of PI3K, PDK and PKC in leukemia cells. Bakkenolide A downregulates activated Akt, GSK and Bad, while upregulates Cyto-c, cleaved Caspase3 and cleaved Caspase7, induces apoptosis (apoptosis) in leukemia cells and thereby inhibits inflammatory responses in leukemia cells. Bakkenolide A significantly slows the growth of subcutaneous leukemia tumors in nude mice. Bakkenolide A is applicable to leukemia-related research .
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Cat. No.: HY-18633
CAS No.: 79183-19-0
Target:  

Apoptosis

Research Areas:  

Cancer

MDK83190 is a potent apoptosis activator, induces Apaf-1 oligomerization, increases procaspase-9 processing and subsequent caspase-3 activation in a cyto c-dependent Manner .
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Cat. No.: HY-111217
CAS No.: 878983-38-1
Purity:  99.23%
Research Areas:  

Neurological Disease Cancer

AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction .
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Cat. No.: HY-146197
CAS No.: 2490538-26-4
Target:  

Apoptosis

Research Areas:  

Cancer

Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes .
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Cat. No.: HY-111217R
CAS No.: 878983-38-1
AKOS-22 (Standard) is the analytical standard of AKOS-22 (HY-111217). This product is intended for research and analytical applications. AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction .
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Cat. No.: HY-103349R
CAS No.: 10129-56-3
Research Areas:  

Cancer

PETCM (Standard) is the analytical standard of PETCM (HY-103349). This product is intended for research and analytical applications. PETCM is an activator of caspase-3 and acts as an cytochrome c (cyto c)-dependent manner. PETCM promotes Apaf-1 oligomerization and induces cell apoptosis in HeLa cells .
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Cat. No.: HY-183366
Target:  

HDAC Caspase Akt

Research Areas:  

Inflammation/Immunology Cancer

HDAC1-IN-14 is an indole-based benzamide selective HDAC1 inhibitor with an IC50 of 77 nM. HDAC1-IN-14 acts as an antiproliferative agent, with GI50 values ranging from nanomolar to low micromolar levels in various cancer cells. HDAC1-IN-14 induces G0-G1 cell cycle arrest in colon cancer cells. HDAC1-IN-14 upregulates the expression of Caspase-3, Cyto-C and Bax, and downregulates the expression of AKT-1. HDAC1-IN-14 can be used in research related to leukemia, non-small cell lung cancer, colon cancer, central nervous system cancer, melanoma, ovarian cancer, renal cancer, prostate cancer and breast cancer .
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Cat. No.: HY-P71040
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SCO1; SCO (Cytochrome Oxidase Deficient, Yeast) Homolog 1; Prev. SCOD1; SCO Cytochrome Oxidase Deficient Homolog 1; SCO1, Cytochrome C Oxidase Assembly Protein; Protein SCO1 Homolog, Mitochondrial; SCO Cytochrome C Oxidase Assembly Protein 1; MC4DN4; Cyto
Species:  
Source:  
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