3 Results for "

Dephostatin

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Dephostatin" in MCE Product Catalog:

Cat. No.: HY-124152
CAS No.: 173043-84-0
Synonyms: Methyl-3,4-Dephostatin
Target:  

MAP3K MAP4K Phosphatase

Research Areas:  

Neurological Disease

3,4-Dephostatin (Methyl-3,4-dephostatin) is an inhibitor of protein-tyrosine phosphatase (PTPase). 3,4-Dephostatin accelerates nerve growth factor (NGF)-induced neurite formation in PC12h cells. 3,4-Dephostatin sustains the NGF-induced tyrosine phosphorylation of proteins, most prominently that of mitogen-activated protein (MAP) kinase. 3,4-Dephostatin also prolongs epidermal growth factor (EGF)-induced tyrosine phosphorylation and activation of MAP kinase .
loading...
    loading...
Cat. No.: HY-N15015
CAS No.: 151606-30-3
Target:  

Phosphatase

Dephostatin is a competitive protein tyrosine phosphatase (PTP) inhibitor that can be isolated from Streptomyces spp., with activity in the micromolar range .
loading...
    loading...
Cat. No.: HY-182483
CAS No.: 237756-11-5
Target:  

Phosphatase

Research Areas:  

Metabolic Disease

Ethyl-3,4-dephostatin is a Protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 0.58 μg/mL. Ethyl-3,4-dephostatin can be used in studies of PTP1B-related enzyme inhibition mechanisms .
loading...
    loading...