Dephostatin
Dephostatin is a competitive protein tyrosine phosphatase (PTP) inhibitor that can be isolated from Streptomyces spp., with activity in the micromolar range.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 151606-30-3
- 分子式: C7H8N2O3
- 分子量:168.15
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
7.7 μM
Compound: Dephostatin
|
Inhibition of human Jurkat cell membrane-derived protein tyrosine phosphatase using o-phospho-L-tyrosine as substrate incubated for 15 mins by by malachite green staining based assay
Inhibition of human Jurkat cell membrane-derived protein tyrosine phosphatase using o-phospho-L-tyrosine as substrate incubated for 15 mins by by malachite green staining based assay
|
[PMID: 27687971] |
化学情報
-
CAS 番号 151606-30-3
-
分子量 168.15
-
分子式 C7H8N2O3
-
SMILES
O=NN(C)C1=CC(O)=CC=C1O
-
Structure Classification
-
Initial Source
Streptomyces
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)