3 Results for "

Eupatorin

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Eupatorin" in MCE Product Catalog:

2
Eupatorin
Eupatorin
0 Images
2 Cited Publications
Cat. No.: HY-N2374
CAS No.: 855-96-9
Category:  

Flavonoids Flavones Cruciferae Isatis tinctoria L. Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

Apoptosis NF-κB MMP Adrenergic Receptor

Eupatorin is an orally active flavonoid with antiproliferative and vasodilatory properties. Eupatorin downregulates the expression levels of NF-κB, MMP9, IL-1β and TNF-α. Eupatorin induces apoptosis, G2/M phase cell cycle arrest, and reactive oxygen species (ROS) production. Eupatorin modulates the activities of muscarinic receptors and β-adrenergic receptors; inhibits sarcoplasmic reticulum calcium release and calcium channels; and activates the NO/sGC/cGMP pathway, indomethacin-sensitive pathway, and potassium channel pathway. Eupatorin exerts cytotoxic effects on cancer cell lines, and is metabolized by CYP1A1 and CYP1 family enzymes to form metabolites with antiproliferative activity. Eupatorin can be used in research related to breast cancer, hypertension, and leukemia .
loading...
    loading...
View All Sizes
Eupatorin-5-methyl ether
Eupatorin-5-methyl ether
0 Images
Cat. No.: HY-N8930
CAS No.: 21764-09-0
Category:  

Flavonoids Flavones Labiatae Plants Swartzia polyphylla DC.

Target:  

Others

Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).
loading...
    loading...
View All Sizes
Eupatorin (Standard)
Eupatorin (Standard)
0 Images
Cat. No.: HY-N2374R
CAS No.: 855-96-9
Category:  

Flavonoids Cruciferae Isatis tinctoria L. Phenols Plants Disease Research Fields Cancer

Target:  

Reference Standards Apoptosis

Eupatorin (Standard) is the analytical standard of Eupatorin. This product is intended for research and analytical applications. Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly(ADP-ribose) polymerase cleavage .
loading...
    loading...
View All Sizes
Assay Types