2. Search Result
Search Result
Results for "

FBXO22

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Protéines recombinantes

2

Antibodies

3

Oligonucleotides

Cat. No. Nom du produit Target Áreas de investigación Chemical Structure
  • HY-163807
    22-SLF

    		PROTACs FKBP Cancer
    22-SLF is a PROTAC degrader, that degrades FK506-binding protein 12 (FKBP12) with a DC50 of 0.5 µM. 22-SLF interacts with C227 and C228 in FBXO22 to induce a ternary complex between FKBP12 and FBXO22, and degrades FKBP12 in a FBXO22-dependent manner. 22-SLF can be used for fundamental cancer research as a probe to study the FBXO22 degradation pathway. (Pink: FKBP12 ligand (HY-114872); Black: Linker (HY-163821); Blue: FBXO22 ligand (HY-163826)) .
    22-SLF
  • HY-173351
    G-6599

    		Epigenetic Reader Domain Cancer
    G-6599 is a monovalent molecular glue-like degrader of SMARCA2/SMARCA4. G-6599 covalently binds to a specific cysteine residue of the E3 ligase FBXO22 in a biotransformation-independent manner, promotes the formation of a ternary complex with SMARCA2/A4, and achieves efficient and specific degradation of the two proteins via the ubiquitin-proteasome pathway. G-6599 is applicable to the research of androgen-dependent prostate cancer and mutant non-small cell lung cancer .
    G-6599
  • HY-RS04799
    FBXO22 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    FBXO22 Human Pre-designed siRNA Set A contains three designed siRNAs for FBXO22 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    FBXO22 Human Pre-designed siRNA Set A
    FBXO22 Human Pre-designed siRNA Set A
  • HY-161794A
    SP3N hydrochloride

    		FKBP Cancer
    SP3N hydrochloride is a specific degrader of the prolyl isomerase (FKBP12). The alkylamine of SP3N hydrochloride is metabolized to a reactive aldehyde (SP3CHO), which recruits the SCF FBXO22 ligase for FKBP12 degradation. SP3N hydrochloride may be used in research for cancer .
    SP3N hydrochloride
  • HY-175756
    SMARCA2/4 degrader-1

    		Molecular Glues SWI/SNF Complex Cancer
    SMARCA2/4 degrader-1 is a SMARCA2/4 molecular glue degrader with a DCAF16 EC50 of 110 nM. SMARCA2/4 degrader-1 covalently adducts at cysteine to form a ternary complex with SMARCA2/4 and recruits CUL4 DCAF16 and CRL1 FBXO22 E3 ligase complexes. SMARCA2/4 degrader-1 induces ubiquitination and proteasomal degradation of SMARCA2/4. SMARCA2/4 degrader-1 can be used for research of SMARCA4-deficient malignancies, non-small cell lung cancer (NSCLC), and colorectal cancer .
    SMARCA2/4 degrader-1
  • HY-RS20155
    Fbxo22 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Fbxo22 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fbxo22 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Fbxo22 Mouse Pre-designed siRNA Set A
    Fbxo22 Mouse Pre-designed siRNA Set A
  • HY-RS26659
    Fbxo22 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Fbxo22 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fbxo22 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Fbxo22 Rat Pre-designed siRNA Set A
    Fbxo22 Rat Pre-designed siRNA Set A
  • HY-161794
    SP3N

    		FKBP Cancer
    SP3N is a specific degrader of the prolyl isomerase (FKBP12). The alkylamine of SP3N is metabolized to a reactive aldehyde (SP3CHO), which recruits the SCF FBXO22 ligase for FKBP12 degradation. SP3N may be used in research for cancer .
    SP3N
  • HY-178321
    UNC10088

    		Molecular Glues Histone Methyltransferase Cancer
    UNC10088 is a molecular glue targeting NSD2. UNC10088 mediates the formation of a stable ternary complex between SCFFBXO22 and the NSD2 PWWP1 domain. UNC10088 promotes ubiquitination of the SCFFBXO22-dependent NSD2 PWWP1 domain through reversible covalent bonding with the C326 region of FBXO22. UNC10088 could be used in cancer research .
    UNC10088

Demande en ligne

Your information is safe with us. * Required Fields.

Civilité

  

Country or Region *

Nom du demandeur *

 

Nom de l'organisation *

Department *

     

Adresse e-mail *

 

Nom du produit *

Cat. No.

  

Requested quantity *

Numéro de téléphone *

     

Remarques

Demande en ligne

Inquiry Information

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent: