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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
FL118
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "FL118" in MCE Product Catalog:
2
2 Cited Publications
Synonyms: 10,11-(Methylenedioxy)-20(S)-camptothecin
FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin (HY-16560) analogue, is a potent and orally active survivin inhibitor. FL118 binds to oncoprotein DDX5 (p68) to dephosphorylates and degrades DDX5. FL118 can be used for the research of cancer .
Synonyms: YL0010014
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FL118-14-Propanol is a FL118 derivative. FL118-14-Propanol synthesized ADC molecule has good anti-tumor effect in mice .
Cat. No.: HY-156856S
Synonyms: YL0010014-d5
Cat. No.: HY-161022A
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FL118-C3-O-C-amide-C-NH2 format is an ADC linker for the synthesis of synthetic antibody conjugate active molecules (ADCs)..
Cat. No.: HY-170868
CAS No.: 3025194-00-4
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CL2A-FL118 is a drug-linker for synthesis of ADC molecule Sac-CL2A-FL118 .
Synonyms: 10,11-(Methylenedioxy)-20(R)-camptothecin
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(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity .
Cat. No.: HY-161022S1
Cat. No.: HY-161022
CAS No.: 2821769-41-7
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FL118-C3-O-C-amide-C-NH2 (compound 6a) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-157419
CAS No.: 2413582-39-3
Synonyms: 7-(4-Ethylphenyl)-FL118
FL77-24, a FL118 analog and apoptosis inducer, possesses antitumor activity, with IC50 values of 99.4 nM, 118 nM, <6.4 nM, 28.5 nM and <6.4 nM in HCT116, HepG2, MCF-7, A549 and HeLa cells, respectively. FL77-24 mainly causes cell cycle arrest in S and G2/M phases .
Cat. No.: HY-161022S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
