6 Results for "

GC-rich

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "GC-rich" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W040129
CAS No.: 7059-24-7
Chromomycin A3 is an inhibitor that selectively binds to GC-rich DNA sequences. Chromomycin A3 targets the DNA minor groove after forming a dimer with Mg 2+. Chromomycin A3 inhibits DNA replication and transcription, blocks the binding of Sp1 transcription factor to target gene promoters, downregulates the expression of anti-apoptotic proteins such as FLIP, Mcl-1, and XIAP, and induces S-phase cycle arrest and caspase-dependent apoptosis in tumor cells. Chromomycin A3 can antagonize oxidative stress induced by glutathione depletion and neuronal apoptosis induced by Camptothecin (HY-15660). Chromomycin A3 can be used in basic research on malignant tumors such as cholangiocarcinoma, and is a potential chemosensitizer and GC-rich region probe .
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Cat. No.: HY-152038
CAS No.: 2863686-82-0
Purity:  98.47%
Research Areas:  

Others

SPEN-IN-1 (compound X1) is an inhibitor of SPEN which is a protein factor with a Kd value of 47 nM. SPEN-IN-1 has high selectivity for RepA, a 431-nucleotide domain in Xist (a non-coding RNA prototype) that comprises 8.5 units of a GC-rich motif responsible for gene silencing .
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Cat. No.: HY-P1911
CAS No.: 254110-79-7
Target:  

EBV

Research Areas:  

Infection

CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 corresponding to amino acids 148-156 of the BRLF1 protein. BRLF1 is a transcriptional activator that binds directly to a GC-rich motif present in some Epstein-Barr virus (EBV) lytic gene promoters .
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Cat. No.: HY-157001
CAS No.: 3056945-65-1
Research Areas:  

Others

7-Deaza-dGTP tetralithium can be used for amplification of GC-rich DNA sequences .
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Cat. No.: HY-W040129R
CAS No.: 7059-24-7
Chromomycin A3 (Standard) is the analytical standard of Chromomycin A3 (HY-W040129). This product is intended for research and analytical applications. Chromomycin A3 is an inhibitor that selectively binds to GC-rich DNA sequences. Chromomycin A3 targets the DNA minor groove after forming a dimer with Mg 2+. Chromomycin A3 inhibits DNA replication and transcription, blocks the binding of Sp1 transcription factor to target gene promoters, downregulates the expression of anti-apoptotic proteins such as FLIP, Mcl-1, and XIAP, and induces S-phase cycle arrest and caspase-dependent apoptosis in tumor cells. Chromomycin A3 can antagonize oxidative stress induced by glutathione depletion and neuronal apoptosis induced by Camptothecin (HY-15660). Chromomycin A3 can be used in basic research on malignant tumors such as cholangiocarcinoma, and is a potential chemosensitizer and GC-rich region probe .
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Cat. No.: HY-P70898
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLF6; B-Cell-Derived Protein 1; Prev. COPEB; GC-rich Binding Factor; Prev. BCD1; Krueppel-Like Factor 6; Prev. ST12; Kruppel Like Factor 6; CPBP; Proto-Oncogene BCD1; PAC1; Suppression Of Tumorigenicity 12 (Prostate); GBF; Core Promoter Element-Binding Pr
Species:  
Source:  
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