2863686-82-0
2863686-82-0
Chemical Structure
SPEN-IN-1
- CAS No.: 2863686-82-0
- Formula:C27H20N4O
- Molecular Weight:416.47
InChIKey: NKMNBWKGYNRJDP-UHFFFAOYSA-N
SMILES: C1(C2=NC3=CC=CC=C3N2)=NNC4=C1C=C(C5=CC=CC(OCC6=CC=CC=C6)=C5)C=C4
Biological Activity: SPEN-IN-1 (compound X1) is an inhibitor of SPEN which is a protein factor with a Kd value of 47 nM. SPEN-IN-1 has high selectivity for RepA, a 431-nucleotide domain in Xist (a non-coding RNA prototype) that comprises 8.5 units of a GC-rich motif responsible for gene silencing[1].
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SPEN-IN-1 | 97.25% | SPEN-IN-1 (compound X1) is an inhibitor of SPEN which is a protein factor with a Kd value of 47 nM. SPEN-IN-1 has high selectivity for RepA, a 431-nucleotide domain in Xist (a non-coding RNA prototype) that comprises 8.5 units of a GC-rich motif responsible for gene silencing. | ||||||||||||||||||||
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References
Keywords
