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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
GPV
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "GPV" in MCE Product Catalog:
Cat. No.: HY-173162
CAS No.: 86383-89-3
Target:
Research Areas:
GPV0057 (Compound 5d) is a selective and potent P-glycoprotein (P-gp) inhibitor. GPV0057 is also a selective potassium channel Kir2.1 activator. GPV0057 competitively binds to the substrate-binding site of P-gp, inhibiting ATP-dependent drug efflux to reverse multidrug resistance in tumor cells. GPV0057 can also stabilizes the open state of Kir2.1 and promotes potassium ion influx. GPV0057 is promising for research of tumors with high P-gp expression, Kir2.1-deficient diseases such as heart failure and Andersen-Tawil Syndrome .
Cat. No.: HY-100838
CAS No.: 117857-95-1
Synonyms: L-CCG III
Target:
Research Areas:
Cat. No.: HY-RS05610
Target:
Research Areas:
GP5 Human Pre-designed siRNA Set A contains three designed siRNAs for GP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-12773A
CAS No.: 86383-32-6
Synonyms: GPV-129 hydrochloride
Target:
Research Areas:
5-Hydroxy Propafenone (hydrochloride) is an inhibitor of cardiac myocyte repolarizing currents. 5-Hydroxy Propafenone is an active metabolite of propafenone. 5-Hydroxy Propafenone (hydrochloride) inhibits transient outward potassium current (Ito) in isolated human arterial myocytes with an IC50 of 1.5 μM. 5-Hydroxy Propafenone (hydrochloride) is potent Ito inhibitor in neonatal rat ventricular myocytes .
Cat. No.: HY-12773AS2
Synonyms: GPV-129-d6 hydrochloride
Cat. No.: HY-169624
CAS No.: 635703-12-7
Target:
Research Areas:
GPV574 is a derivative of the antiarrhythmic compound propafenone, capable of inhibiting HERG channels (IC50 = 5.04 μM).
Cat. No.: HY-P705395
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GP5; Glycoprotein 5; Glycoprotein V Platelet; GPV; Platelet Glycoprotein V; Glycoprotein V (Platelet); CD42d; CD42d Antigen
Cat. No.: HY-RS17795
Target:
Research Areas:
Gp5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gp5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-12773AS
CAS No.: 1215370-87-8
Synonyms: GPV-129-d5 hydrochloride
Cat. No.: HY-12773AS1
CAS No.: 1188265-48-6
Synonyms: GPV-129-d5-1 hydrochloride
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
