GPV574
GPV574 is a derivative of the antiarrhythmic compound propafenone, capable of inhibiting HERG channels (IC50 = 5.04 μM).
For research use only. We do not sell to patients.
- CAS No.: 635703-12-7
- Formula: C23H30N2O3
- Molecular Weight:382.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 5.04 μM (HERG)[1].
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDR | EC50 |
1.349 μM
Compound: 123
|
Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay
Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay
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[PMID: 17352460] |
Chemical Information
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CAS No. 635703-12-7
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Molecular Weight 382.50
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Formula C23H30N2O3
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SMILES
O=C(C)C1=CC=C(C=C1)OCC(CN2CCN(CC2)C3=CC=CC(C)=C3C)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)