Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
HACE1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "HACE1" in MCE Product Catalog:
Cat. No.: HY-RS05987
Target:
Research Areas:
HACE1 Human Pre-designed siRNA Set A contains three designed siRNAs for HACE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22546
Target:
Research Areas:
Hace1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hace1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29066
Target:
Research Areas:
Hace1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hace1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-149288
Research Areas:
hAChE/hBACE-1-IN-2 is a potent, orally active, blood-brain barrier transboundary triple inhibitor of hAChE, hBChE, and HACE-1 with IC50s of 0.113 μM, 1.48 μM and 0.38 μM, respectively. hAChE/hBACE-1-IN-2 has antioxidant activity. hAChE/hBACE-1-IN-2 also inhibits Aβ11-42 aggregation. hAChE/hBACE-1-IN-2 can be used to study Alzheimer's disease [1].
Cat. No.: HY-P701526
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HACE1; HECT Domain And Ankyrin Repeat-Containing E3 Ubiquitin-Protein Ligase 1; HECT Domain And Ankyrin Repeat Containing E3 Ubiquitin Protein Ligase 1; HECT-Type E3 Ubiquitin Transferase; KIAA1320; Alternative Protein HACE1; HECT-Type E3 Ubiquitin Transf
Cat. No.: HY-175521
Research Areas:
HIF-1α-IN-8 is an orally active HIF-1α inhibitor, with an IC50 of 2.02 μM. HIF-1α-IN-8 significantly suppresses the expression of inflammation factors of IL-6 and NO, reduces hypoxia-induced ROS production and apoptosis in C8-D1A cells. HIF-1α-IN-8 inhibits HIF-1α/IKKα/NF-κB signaling pathway and reduces the expression of blood-brain barrier permeability-related proteins. HIF-1α-IN-8 reduces brain water content and oxidative stress level in mice with high altitude cerebral edema (HACE) model. HIF-1α-IN-8 can be used for the study of high altitude cerebral edema (HACE) .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
