2 Results for "

HB3 strain

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "HB3 strain" in MCE Product Catalog:

Cat. No.: HY-134914
CAS No.: 66508-53-0
Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DOXP reductoisomerase). Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC50s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin (HY-B1455), and ameliorates malaria in mouse model .
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Cat. No.: HY-106515
CAS No.: 74129-03-6
Synonyms: WR228258
Target:  

Parasite

Research Areas:  

Infection

Tebuquine (WR228258), a 4-aminoquinoline, is a potent antimalarial agent. Tebuquine is active against the Chloroquine (HY-17589A) sensitive HB3 strain and the Chloroquine resistant K1 strain of Plasmodium falciparum with IC50s of 0.9 nM and 20.8 nM, respectively .
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