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Pathways Recommended: Cell Cycle/DNA Damage
Results for "

HCMV DNA polymerase

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131606B
    Cidofovir diphosphate tritriethylamine

    		Drug Metabolite DNA/RNA Synthesis Infection
    Cidofovir diphosphate tri triethylamine is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate tri triethylamine is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively .
    Cidofovir diphosphate tritriethylamine
  • HY-131606
    Cidofovir diphosphate

    		HSV CMV DNA/RNA Synthesis Infection
    Cidofovir diphosphate is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively .
    Cidofovir diphosphate
  • HY-170547
    DNA polymerase-IN-6

    		DNA/RNA Synthesis HSV EBV CMV Infection
    DNA polymerase-IN-6 is an antiviral agent and a DNA polymerase inhibitor. DNA polymerase-IN-6 inhibits the replication of HCMV, HSV-1, HSV-2 and EBV. DNA polymerase-IN-6 exhibits low cytotoxicity in mammalian cells. DNA polymerase-IN-6 can be used in research related to viral infections .
    DNA polymerase-IN-6
  • HY-W150426
    Naphthol AS-BS

    		CMV DNA/RNA Synthesis Infection
    Naphthol AS-BS (Compound 1) is a human cytomegalovirus (HCMV) DNA polymerase alpha inhibitor with an IC50 of 12 μM. Naphthol AS-BS can be used for the research of infection .
    Naphthol AS-BS
  • HY-170547A
    DNA polymerase-IN-6 formic

    		HSV CMV EBV DNA/RNA Synthesis Infection
    DNA polymerase-IN-6 formic is an antiviral agent and a DNA polymerase inhibitor. DNA polymerase-IN-6 formic inhibits the replication of HCMV, HSV-1, HSV-2 and EBV. DNA polymerase-IN-6 formic exhibits low cytotoxicity in mammalian cells. DNA polymerase-IN-6 formic can be used in research related to viral infections .
    DNA polymerase-IN-6 formic
  • HY-185150
    PMEG

    9-(2-Phosphonylmethoxy)ethylguanine

    		 DNA/RNA Synthesis CMV Infection Inflammation/Immunology Cancer
    PMEG is a nuclear DNA polymerases α, δ, and ε inhibitor that causes DNA chain termination, inhibits DNA synthesis, induces cytotoxicity in dividing cells. PMEG is an acyclic nucleotide phosphonate that forms an active phosphorylated metabolite, PMEG diphosphate, within cells. PMEG has activity against leukemia and melanoma in rodent models. PMEG has poor cell permeability; its prodrug is Rabacfosadine (GS-9219) (HY-13640). PMEG shows antiviral activity against against various DNA virus infections including murine cytomegalovirus (MCMV) and human cytomegalovirus (HCMV). PMEG can be used for the research of non-hodgkin's lymphoma [1][2].
    PMEG

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