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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
HIV-1 reverse transcriptase p66 domain
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "HIV-1 reverse transcriptase p66 domain" in MCE Product Catalog:
Cat. No.: HY-184492
CAS No.: 3069129-78-5
Target:
Research Areas:
HIV-IN-14 is an agent that binds to the HIV-1 reverse transcriptase p66 domain (monomeric GAG-POL), and also acts as a selective cytotoxic agent. HIV-IN-14 promotes GAG-POL dimerization, which in turn leads to premature activation of intracellular viral protease. HIV-IN-14 selectively kills HIV-infected cells expressing GAG-POL without exerting cytotoxicity on non-HIV-infected cells. HIV-IN-14 can be used in the research of HIV infection, acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) .
Cat. No.: HY-184924
CAS No.: 3102264-65-0
Target:
Research Areas:
HIV-IN-15 is a HIV-infected cell killer, with an EC50 of 20 nM in the HIV-TACK assay. HIV-IN-15 binds to the reverse transcriptase p66 domain of monomeric GAG-POL, accelerates the dimerization process, and selectively kills HIV-infected cells expressing GAG-POL, with no cytotoxicity against HIV-uninfected cells. HIV-IN-15 can be used for research on HIV infection, acquired immunodeficiency syndrome (AIDS), or AIDS-related complex (ARC) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
