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Results for "

HLA-E

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Peptides

1

Inhibitory Antibodies

11

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS06215
    HLA-E Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    HLA-E Human Pre-designed siRNA Set A contains three designed siRNAs for HLA-E gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HLA-E Human Pre-designed siRNA Set A
    HLA-E Human Pre-designed siRNA Set A
  • HY-P991610
    S-095029

    Sym025

    		 C-type Lectin-like Receptors (CTLRs) Cancer
    S-095029 is a humanized IgG1 monoclonal antibody inhibitor targeting NKG2A. S-095029 significantly attenuates Fc-effector functions, inhibits the interaction with its ligand HLA-E, and increases the antibody-dependent cellular cytotoxicity mediated by other Fc-competent mAbs. S-095029 has a potent antitumor activity with enhancement of killing activity and cytokine secretion (IFNγ, TNF-α and CXCL9) of NK and γδ T-cells in co-culture with cancer cells .
    S-095029
  • HY-P11340
    VMAPRTLFL

    		MHC Infection Inflammation/Immunology
    VMAPRTLFL is a 9-mer peptide derived from the signal peptide of HLA-G and can serve as a peptide ligand for HLA-E. VMAPRTLFL plays a crucial role in regulating the functions of adaptive natural killer (NK) cells. Specifically, VMAPRTLFL enriches FcεRγ - adaptive NK cells, upregulates the expression of CD25, and enhances their proliferative activity, antibody-dependent cellular cytotoxicity (ADCC), and IFN-γ release. VMAPRTLFL can be used in research related to human cytomegalovirus (HCMV) infection, transplant rejection, and pregnancy immunity .
    VMAPRTLFL

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