3 Results for "

K-145

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "K-145" in MCE Product Catalog:

Cat. No.: HY-15779
CAS No.: 1309444-75-4
Target:  

SphK Apoptosis

Research Areas:  

Cancer

K145 is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM. K145 is inactive against SphK1 and other protein kinases. K145 induces cell apoptosis and has potently antitumor activity .
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6
6 Publications Verification
Cat. No.: HY-15779A
CAS No.: 1449240-68-9
Purity:  99.62%
Target:  

SphK Apoptosis

Research Areas:  

Cancer

K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity .
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1
1 Cited Publications
Cat. No.: HY-P79127
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC11; Siglec-11; Sialic Acid Binding Ig Like Lectin 11; Sialic Acid Binding Ig-Like Lectin 11; Sialic Acid-Binding Ig-Like Lectin 11; Sialic Acid-Binding Lectin 11
Species:  
Source:  
CHO
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