22 Results for "

KISS

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "KISS" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P2161B
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .
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3
3 Cited Publications
Cat. No.: HY-P0076
CAS No.: 1234319-68-6
Synonyms: MVT-602
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

TAK-448 (MVT-602) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM .
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3
3 Cited Publications
Cat. No.: HY-P0076A
CAS No.: 1470374-22-1
Synonyms: MVT-602 acetate
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM .
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3
3 Cited Publications
Cat. No.: HY-P1022
CAS No.: 374683-24-6
Synonyms: Metastin(human)
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

Kisspeptin-54(human) (Metastin(human)) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) binds to rat and human GPR54 receptors with Ki values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) inhibits tumor metastasis and stimulates the secretion of gonadotropin (LH) and testosterone .
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3
3 Cited Publications
Cat. No.: HY-P1197
CAS No.: 478507-53-8
Kisspeptin-10 (mouse, rat) is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10 (mouse, rat) is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound .
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3
3 Cited Publications
Cat. No.: HY-P1197A
Kisspeptin-10 (mouse, rat) TFA is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10 (mouse, rat) TFA is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 (mouse, rat) TFA reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound .
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3
3 Cited Publications
Cat. No.: HY-P1022A
Synonyms: Metastin(human) TFA
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

Kisspeptin-54(human) TFA (Metastin(human) TFA) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) TFA binds to rat and human GPR54 receptors with Ki values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) TFA hinders tumor metastasis and stimulates gonadotropin secretion .
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Cat. No.: HY-P10489
CAS No.: 374675-19-1
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

Kisspeptin-14 human is a peptide hormone encoded by the KiSS-1 gene. Kisspeptin-14 human, along with several other similar peptide hormones, is produced from a common precursor protein by cleavage by different proteases. Kisspeptin-14 human is an endogenous ligand of KISS1R. Kisspeptin-14 human has the same receptor binding efficiency and potency as full-length kisspeptin. Kisspeptin-14 human binds to its receptor GPR54 and is able to activate this G protein-coupled receptor and activate multiple intracellular signaling pathways. Kisspeptin-14 human can be used to study reproductive development and tumor metastasis .
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Cat. No.: HY-P1196A
CAS No.: 1848962-29-7
Target:  

Kisspeptin Receptor

Research Areas:  

Cardiovascular Disease

Kisspeptin 234 TFA, is a 10 amino acid peptide as well as a kisspeptin receptor (KISS1, GPR54) antagonist. Kisspeptin 234 TFA is an analog of Kisspeptin 10 .
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Cat. No.: HY-P10256A
Research Areas:  

Endocrinology

Kiss2 peptide acetate is the acetate form of Kiss2 pepride (HY-P10256). Kiss2 peptide acetate is a positive regulator of reproduction. Kiss2 peptide acetate binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) .
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Cat. No.: HY-RS07316
Research Areas:  

Others

KISS1R Human Pre-designed siRNA Set A contains three designed siRNAs for KISS1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P2161
CAS No.: 872719-49-8
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

TAK-683 is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .
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Cat. No.: HY-P2191
CAS No.: 872717-97-0
Target:  

Kisspeptin Receptor

Research Areas:  

Endocrinology

KISS1-305, the Metastin/Kisspeptin analog, is a prototype peptide and a chemical probe. KISS1-305 has suboptimal KISS1R agonistic activity, and resists plasma protease degradation .
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Cat. No.: HY-P1196
CAS No.: 1145998-81-7
Target:  

Kisspeptin Receptor

Research Areas:  

Cardiovascular Disease

Kisspeptin 234, is a 10 amino acid peptide as well as a kisspeptin receptor (KISS1, GPR54) antagonist. Kisspeptin 234 is an analog of Kisspeptin 10 .
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Cat. No.: HY-P10256
CAS No.: 1111070-93-9
Research Areas:  

Endocrinology

Kiss2 peptide is a positive regulator of reproduction. Kiss2 peptide binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) .
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Cat. No.: HY-RS07315
Research Areas:  

Others

KISS1 Human Pre-designed siRNA Set A contains three designed siRNAs for KISS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS18527
Research Areas:  

Others

Kiss1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kiss1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS07317
Research Areas:  

Others

Kiss1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kiss1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS07318
Research Areas:  

Others

Kiss1r Rat Pre-designed siRNA Set A contains three designed siRNAs for Kiss1r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P2161A
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .
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