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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
KLK6
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "KLK6" in MCE Product Catalog:
Cat. No.: HY-RS07384
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KLK6 Human Pre-designed siRNA Set A contains three designed siRNAs for KLK6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17290
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Klk6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Klk6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23745
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Klk6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Klk6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-182600
CAS No.: 2370980-52-0
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KLK6-IN-1 is a reversible small‑molecule inhibitor of KLK6, KLK1, and plasmin. KLK6-IN-1 shows IC50 values of 1.57 μM (KLK6), 5.1 μM (KLK1), 7.4 μM (plasmin), and Ki values of 0.8 μM (KLK6), 2.4 μM (KLK1), 1.3 μM (plasmin). KLK6-IN-1 is highly selective for KLK6 and its proteolytic network. KLK6-IN-1 induces oligodendrocyte differentiation by promoting oligodendrocyte precursor cell maturation. KLK6-IN-1 can be used for the research of multiple sclerosis .
Cat. No.: HY-124610
CAS No.: 2244425-14-5
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DKFZ-633 is a potent KLK6 inhibitor and KLK6-specific probe with an IC50 of 250 nM against human KLK6. DKFZ-633 covalently labels active KLK6 in a specific manner, and successfully pulls down and captures endogenous active KLK6 from cell-conditioned media. DKFZ-633 serves as a critical tool for investigating the function of KLK6 and its regulatory mechanisms in head and neck cancer .
Cat. No.: HY-124714
CAS No.: 2222059-70-1
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DKFZ-251 is a kininogenase-related peptidase KLK6 inhibitor (IC50=0.47 μM), and also exhibits certain inhibitory activity against KLK5 and KLK7 (IC50 values are 1.1 nM and 73 nM, respectively). DKFZ-251 transiently acylates the catalytic serine of KLK6 to form a long-lived acyl-enzyme complex that inhibits enzyme function. DKFZ-251 is a phenotypic modulator that alters cell proliferation capacity and regulates epithelial-mesenchymal transition (EMT). DKFZ-251 can be used in research related to head and neck cancer .
Cat. No.: HY-RS07373
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KLK1 Human Pre-designed siRNA Set A contains three designed siRNAs for KLK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P73262
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLK1; Kallikrein 1, Renal/Pancreas/Salivary, Isoform CRA_c; Kallikrein 1; Kallikrein 1, Renal/Pancreas/Salivary, Isoform CRA_a; KLK6; Kallikrein 1 Isoform 3 Preproprotein; Kidney/Pancreas/Salivary Gland Kallikrein; Kallikrein Serine Protease 1; Kallikrein
Cat. No.: HY-P70887
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLK6; Zyme; Prev. PRSS18; Kallikrein-Related Peptidase 6 Transcript Variant 10; Prev. PRSS9; Kallikrein-Related Peptidase 6 Transcript Variant 11; Neurosin; Kallikrein-Related Peptidase 6 Transcript Variant 6; Bssp; Kallikrein-Related Peptidase 6 Transcri
Cat. No.: HY-P70144
Purity: ≥ 95%, as determined by reducing SDS-PAGE. ≥ 95%, as determined by HPLC.
Synonyms: KLK1; Kallikrein 1, Renal/Pancreas/Salivary, Isoform CRA_c; Kallikrein 1; Kallikrein 1, Renal/Pancreas/Salivary, Isoform CRA_a; KLK6; Kallikrein 1 Isoform 3 Preproprotein; Kidney/Pancreas/Salivary Gland Kallikrein; Kallikrein Serine Protease 1; Kallikrein
Cat. No.: HY-P70302
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLK1; Kallikrein 1, Renal/Pancreas/Salivary, Isoform CRA_c; Kallikrein 1; Kallikrein 1, Renal/Pancreas/Salivary, Isoform CRA_a; KLK6; Kallikrein 1 Isoform 3 Preproprotein; Kidney/Pancreas/Salivary Gland Kallikrein; Kallikrein Serine Protease 1; Kallikrein
Cat. No.: HY-RS18037
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Klk1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Klk1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
