1 Result for "

Kansuinine B

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Kansuinine B" in MCE Product Catalog:

Kansuinine B
Kansuinine B
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Cat. No.: HY-126420
CAS No.: 57685-46-8
Purity:  ≥99.0%
Category:  

Terpenoids Euphorbia kansui T. N. Liou ex S. B. Ho Euphorbiaceae Diterpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

SARS-CoV Interleukin Related ERK STAT

Kansuinine B is a natural diterpenoid compound with anti-inflammatory, anti-cancer and anti-viral activities, which can be isolated from the roots of Euphorbia kansui. Kansuinine B induces sustained ERK1/2 activation, inhibits IL-6-induced Stat3 activation and tyrosine phosphorylation, and enhances serine phosphorylation of Stat3. Kansuinine B negatively regulates the IL-6 signaling pathway by upregulating the expression of SOCS-3. Kansuinine B promotes the proliferation of mouse splenic lymphocytes in vitro and stimulates rat peritoneal macrophages to produce NO. Kansuinine B can be used in studies related to liver cancer and COVID-19 .
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