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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

LU-1 cells

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Drug Derivative (1) FAP (1) Radionuclide-Drug Conjugates (RDCs) (1)
By Research Areas:	Cancer (4)

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Targets Recommended: Nuclear Factor of activated T Cells (NFAT) TREM receptor CD44

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-164725

FAPI-mFS	Radionuclide-Drug Conjugates (RDCs) FAP	Cancer
FAPI-mFS is an irreversible fibroblast activation protein (FAP) inhibitor, that enhances the uptake and retention time in cancer cells through its covalent binding property for FAP. FAPI-mFS can be used for cancer imaging the therapy, when labeled with radioactive 68Ga or 177Lu . FAPI-mFS can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-122783

Isogambogic acid	Antibiotic	Cancer
Isogambogic acid is an antibiotic and anti-cancer agent which efficiently elicit cell death in LLC and SK-LU-1 within a low micromolar range with IC₅₀s of 2.26 μM and 2.02 μM. Isogambogic acid can be used for cancer research .

HY-N7340

Withaperuvin C	Others	Cancer
Withaperuvin C is a withanolide that can be isolated from Physalis Minima. Withaperuvin C has moderate cytotoxicity against cancer cells such as HepG2, SK-LU-1, and MCF7 cells (IC₅₀: 19.5, 14.65, 11.74 μg/mL) .

HY-N17410

Umbellatolide A	Drug Derivative	Others
Umbellatolide A is an 11-noriridoid found in the aerial parts of Morinda umbellata. Umbellatolide A shows no significant cytotoxic activity against human cancer cells .

HY-N17444

3β-Hydroxy-24-methylenecholest-5-en-7-one	Others	Others
3β-Hydroxy-24-methylenecholest-5-en-7-one (Compound 4) is a steroid found in the soft coral Sinularia nanolobata. 3β-Hydroxy-24-methylenecholest-5-en-7-one does not exhibit cytotoxic activity against human cancer cells .

HY-N17957

Homoisopogon B	Others	Cancer
Homoisopogon B is a homoisoflavane found in the tubers of Ophiopogon japonicus. Homoisopogon B shows cytotoxic activity against cancer cells. Homoisopogon B can be used for the research of cancer, such as human lung adenocarcinoma and human melanoma .

Cat. No.	Product Name	Target	Research Area

HY-164725

FAPI-mFS	Radionuclide-Drug Conjugates (RDCs) FAP	Cancer
FAPI-mFS is an irreversible fibroblast activation protein (FAP) inhibitor, that enhances the uptake and retention time in cancer cells through its covalent binding property for FAP. FAPI-mFS can be used for cancer imaging the therapy, when labeled with radioactive 68Ga or 177Lu . FAPI-mFS can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

Isogambogic acid	Structural Classification Xanthones Guttiferae Phenols Plants Garcinia hanburyi Hook. f. Source Classification	Antibiotic
Isogambogic acid is an antibiotic and anti-cancer agent which efficiently elicit cell death in LLC and SK-LU-1 within a low micromolar range with IC₅₀s of 2.26 μM and 2.02 μM. Isogambogic acid can be used for cancer research .

Withaperuvin C	Physalis minima Linn. Plants Solanaceae Steroids Source Classification	Others
Withaperuvin C is a withanolide that can be isolated from Physalis Minima. Withaperuvin C has moderate cytotoxicity against cancer cells such as HepG2, SK-LU-1, and MCF7 cells (IC₅₀: 19.5, 14.65, 11.74 μg/mL) .

Umbellatolide A	Morinda umbellata L. Structural Classification Natural Products Rubiaceae Plants Source Classification	Drug Derivative
Umbellatolide A is an 11-noriridoid found in the aerial parts of Morinda umbellata. Umbellatolide A shows no significant cytotoxic activity against human cancer cells .

3β-Hydroxy-24-methylenecholest-5-en-7-one	Triterpenes Structural Classification Animals Terpenoids Source Classification	Others
3β-Hydroxy-24-methylenecholest-5-en-7-one (Compound 4) is a steroid found in the soft coral Sinularia nanolobata. 3β-Hydroxy-24-methylenecholest-5-en-7-one does not exhibit cytotoxic activity against human cancer cells .

Homoisopogon B	Structural Classification Flavonoids Plants Other Flavonoids Asparagaceae Juss. Source Classification	Others
Homoisopogon B is a homoisoflavane found in the tubers of Ophiopogon japonicus. Homoisopogon B shows cytotoxic activity against cancer cells. Homoisopogon B can be used for the research of cancer, such as human lung adenocarcinoma and human melanoma .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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LU-1 cells

Inhibitors & Agonists

Peptides

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Natural
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