3 Results for "

Lactacystin

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Lactacystin" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-16594
CAS No.: 133343-34-7
Lactacystin is a potent, orally active, irreversible, cell-permeable, selective 20S proteasome inhibitor (IC50 = 4.8 μM). Lactacystin also inhibits the lysosomal enzyme cathepsin A. Lactacystin inhibits cell growth and induces apoptosisand cell cycle arrest, and has antiviral and antioxidative activity. Lactacystin induces neurite outgrowth and hypertension. Lactacystin has the potential for the research of cancer, Neurological Disease, hypertension and Malaria, and so on [2] [6] .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-131036
CAS No.: 64821-19-8
Purity:  99.25%
Target:  

Monoamine Oxidase

Research Areas:  

Neurological Disease

MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain selective irreversible MAO-A (IC50=37 nM) and MAO-B (IC50=57 nM) inhibitor. MAO-IN-M30 dihydrochloride is a potent iron chelator and radical scavenger. MAO-IN-M30 dihydrochloride has a neuroprotective effect against Dexamethasone-induced brain cell apoptosis. MAO-IN-M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's disease . MAO-IN-M30 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
loading...
    loading...
Cat. No.: HY-108549
CAS No.: 154226-60-5
Purity:  ≥98.0%
Synonyms: Omuralide; β-ClastoLactacystin
Target:  

Proteasome

Clasto-Lactacystin β-lactone, a natural active metabolite of lactacystin, which is a metabolite of Streptomyces, acts as an irreversible 20S proteasome inhibitor.
loading...
    loading...