19 Results for "

Lrrc15

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Lrrc15" in MCE Product Catalog:

Cat. No.: HY-P99899
CAS No.: 2052591-32-7
Synonyms: PR-1498487

Target:  

ADC Antibodies

Research Areas:  

Cancer

Samrotamab (PR-1498487) is a humanized IgG1-κ chimeric monoclonal antibody targeting LRRC15, with a Kd of 5.42 nM for human LRRC15. Samrotamab can be used to synthesize antibody-drug conjugates (ADC). Samrotamab disrupts the LRRC15-SCG5 signaling module, binds to a membrane-proximal conformational epitope within the C-terminal leucine-rich repeat region of LRRC15, and binds to the lateral edge of the LRR solenoid while leaving the canonical concave β-sheet surface fully exposed. Samrotamab reduces the viability of bladder cancer cells, inhibits clonogenic growth, impairs cell migration, and compromises cell invasion. Samrotamab induces compensatory upregulation of LRRC15 transcripts while suppressing the expression of SCG5 mRNA. Samrotamab is applicable to research related to urothelial carcinoma, sarcoma, osteosarcoma, and undifferentiated pleomorphic sarcoma .
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Cat. No.: HY-RS07808
Research Areas:  

Others

LRRC15 Human Pre-designed siRNA Set A contains three designed siRNAs for LRRC15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17927
Research Areas:  

Others

Lrrc15 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lrrc15 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24397
Research Areas:  

Others

Lrrc15 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lrrc15 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P83437
Synonyms: LIB

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P701020
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Species:  
Source:  
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Cat. No.: HY-P78486
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Species:  
Source:  
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Cat. No.: HY-P72512
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Species:  
Source:  
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Cat. No.: HY-P78695
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Species:  
Source:  
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Cat. No.: HY-P705057
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Species:  
Source:  
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Cat. No.: HY-P705284
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Species:  
Rat
Source:  
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Cat. No.: HY-P83437A
Synonyms: LIB

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P78172
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Species:  
Source:  
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Cat. No.: HY-P704768
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Source:  
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Cat. No.: HY-P78844
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Species:  
Source:  
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Cat. No.: HY-P700892
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Source:  
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Cat. No.: HY-P76480
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Species:  
Source:  
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Cat. No.: HY-P78845
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Source:  
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Cat. No.: HY-P705181
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Lrrc15; Leucine-Rich Repeat-Containing Protein 15; Leucine Rich Repeat Containing 15; HLib; LIB; Leucine-Rich Repeat Protein Induced By Beta Amyloid; Leucine-Rich Repeat Protein Induced By Beta-Amyloid Homolog
Source:  
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