LRRC15 Antibody (YA3182)
(Synonyms: LIB)
Based on 1 Customer Validation
LRRC15 Antibody (YA3182) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LRRC15.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-1:5000 | 1:50-1:100 |
Product Details
LRRC15 Antibody (YA3182) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LRRC15.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 64 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 64 kDa
Entrez Gene: 131578 Human ; 74488 Mouse ; 246296 Rat
SwissProt: Q8TF66 Human ; Q80X72 Mouse ; Q8R5M3 Rat
OMIM: 619327 Human
A synthetic peptide of human LRRC15
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
(Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein (PubMed:36228039, PubMed:36735681, PubMed:36757924). Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells (PubMed:36228039, PubMed:36757924)
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:Expressed in brain and placenta (PubMed:11785964) . Expressed in lung fibroblasts (PubMed:36228039, PubMed:36757924) . Expressed in chodrocytes (PubMed:34702854)
Induction:In fiboblasts, expression is strongly induced by TGFB1 (PubMed:36735681, PubMed:36757924) . In chodrocytes, expression is induced by IL1B (PubMed:34702854) ; (Microbial infection) In alveolar cells and fibroblasts, expression is induced by Sars-CoV-2 infection -
Isoforms & Post-Translational Modification
Q8TF66 has 2 isomers: Q8TF66-1: 64366 Da (predicted); Q8TF66-2: 65022 Da (predicted).
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Subunit
(Microbial infection) Interacts with human coronavirus SARS-CoV-2 spike protein (via RBD domain); the interaction is direct and sequesters virions at the cell surface
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SwissProt ID
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Synonyms
LIB
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Research Field
Neuroscience
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