2. Gene
  3. LRRC15 - leucine rich repeat containing 15 Gene

LRRC15 - leucine rich repeat containing 15 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as LIB

Gene ID: 131578 | Gene type: protein coding

About LRRC15

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:194,355,249-194,369,743 (from NCBI)

This gene has 2 transcripts (splice variants), 112 orthologues and 22 paralogues. Broad expression in endometrium (RPKM 1.9), gall bladder (RPKM 1.2) and 15 other tissues.

Summary

Enables collagen binding activity; fibronectin binding activity; and laminin binding activity. Involved in negative regulation of protein localization to plasma membrane; positive regulation of cell migration; and receptor-mediated virion attachment to host cell. Located in extracellular exosome. Colocalizes with collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

LRRC15 Products(2)

mRNA Protein Name
NM_001135057.3 NP_001128529.2 leucine-rich repeat-containing protein 15 isoform a precursor
NM_130830.5 NP_570843.2 leucine-rich repeat-containing protein 15 isoform b precursor

LRRC15 Protein Structure

LRR_8

LRR_8: Leucine rich repeat (81 - 137)

LRR_1

LRR_1: Leucine Rich Repeat (150 - 172)

LRR_8

LRR_8: Leucine rich repeat (175 - 233)

LRR_4

LRR_4: Leucine Rich repeats (2 copies) (246 - 286)

LRR_8

LRR_8: Leucine rich repeat (293 - 353)

LRR_8

LRR_8: Leucine rich repeat (366 - 423)

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  • 581 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat-containing protein 15

hLib

Recombinant LRRC15 Proteins

Cat. No. Product Name Accession Purity
HY-P72512 LRRC15 Protein, Human (HEK293, His) Q8TF66 (Y22-G538) ≥95%
HY-P76480 LRRC15 Protein, Human (HEK293, Fc) Q8TF66 (Y22-G538) ≥95%
HY-P78172 LRRC15 Protein, Human (Biotinylated, HEK293, His-Avi) Q8TF66 (Y22-G538) ≥95%
HY-P78486 LRRC15 Protein, Human (HEK293, His-Avi) Q8TF66 (Y22-G538) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07808 LRRC15 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus LRRC15 VGNC VGNC:97483
Bos taurus LRRC15 VGNC VGNC:31001
Rattus norvegicus LRRC15 RGD RGD:70551
Macaca mulatta LRRC15 VGNC VGNC:74322
Canis familiaris LRRC15 VGNC VGNC:42786
Mus musculus LRRC15 MGD MGI:1921738
Macaca fascicularis LRRC15 NCBI
Others LRRC15 NCBI