7 Results for "

Maxi-K

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Maxi-K" in MCE Product Catalog:

Cat. No.: HY-N6688
CAS No.: 12771-72-1
Verruculogen is a tremorgenic mycotoxin and inhibitor of the M phase of the mammalian cell cycle. Verruculogen is produced by Penicillium and Aspergillus species. Verruculogen enhances the binding of ChTX to maxi-k channels with a K1/2 value of 170 nM. Verruculogen inhibits the amplitude of Ca 2+-activated K + currents. Verruculogen induces severe tremors in infected animals .
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Cat. No.: HY-176856
CAS No.: 2748705-69-1
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Maxi-K modulator 1 (Example 1) is a Maximum conductance calcium-activated potassium (Maxi-K) channel modulator. Maxi-K modulator 1 has a potent stimulating effect on Maxi-K channel activity. Maxi-K modulator 1 can be used for fragile X syndrome research .
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Cat. No.: HY-19397
CAS No.: 275375-69-4
Research Areas:  

Neurological Disease

BMS-223131 (Compound 1) is a potent maxi-K potassium channel opener. BMS-223131 has a strong inhibitory effect on the CYP2C9 enzyme (IC50 = 1.7 μM) and also shows varying degrees of inhibition on other common CYP enzymes such as CYP1A2, CYP2C19, CYP2D6, and CYP3A4. BMS-223131 can enhance the outward current mediated by maxi-K, by promoting K + efflux to hyperpolarize the cell membrane and reducing Ca 2+ influx. BMS-223131 can be used for the research of neurological disease, such as stroke .
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Cat. No.: HY-N19650
CAS No.: 11024-55-8
Paspalicine is an indole diterpenoid fungal metabolite with no tremorgenic activity in animals. Paspalicine targets the large-conductance calcium-activated potassium (maxi-K) channel, blocks channel activity, and modulates the binding of Charybdotoxin (HY-P0191) to the maxi-K channel via a positive allosteric mechanism that enhances toxin binding. Paspalicine can be used in studies related to ryegrass staggers .
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Cat. No.: HY-RS20560
Research Areas:  

Others

Kcnma1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kcnma1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS27069
Research Areas:  

Others

Kcnma1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Kcnma1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS07164
Research Areas:  

Others

KCNMA1 Human Pre-designed siRNA Set A contains three designed siRNAs for KCNMA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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