6 Results for "

Moexiprilat

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Moexiprilat" in MCE Product Catalog:

Art. -Nr.: HY-B0378A
CAS. Nr.: 82586-52-5
Synonyms: RS-10085
Moexipril hydrochloride (RS-10085) is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). Moexipril hydrochloride exhibits antihypertensive and neuroprotective effects - .
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Art. -Nr.: HY-A0114
CAS. Nr.: 103775-14-0
Synonyms: RS 10029
Forschungsgebiete:  

Cardiovascular Disease

Moexiprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50=2.1 nM) and an active metabolite of the prodrug Moexipril (HY-117281). It is formed from moexipril in vivo by side chain ester hydrolysis. Moexiprilat (10 nM) prevents the estrone- or angiotensin II-stimulated proliferation of primary neonatal rat cardiac fibroblasts. It reduces mean arterial blood pressure and increases the levels of atrial natriuretic peptide, a marker of hypertension, in ovariectomized mice when administered at a dose of 50 mg/kg per day.
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Art. -Nr.: HY-117281
CAS. Nr.: 103775-10-6
Moexipril is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). Moexipril exhibits antihypertensive and neuroprotective effects - .
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Art. -Nr.: HY-A0114S
CAS. Nr.: 1356840-08-8
Moexiprilat-d5 is deuterium labeled Moexiprilat.
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Art. -Nr.: HY-117281S1
Moexipril-d3 is deuterated labeled Moexipril (HY-117281). Moexipril is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila hydrochloride. Moexipril exhibits antihypertensive and neuroprotective effects - .
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Art. -Nr.: HY-B0378AR
CAS. Nr.: 82586-52-5
Synonyms: RS-10085 (Standard)
Moexipril (hydrochloride) (Standard) is the analytical standard of Moexipril (hydrochloride). This product is intended for research and analytical applications. Moexipril hydrochloride (RS-10085) is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). Moexipril hydrochloride exhibits antihypertensive and neuroprotective effects - .
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