1 Result for "

Monotropitoside

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Monotropitoside" in MCE Product Catalog:

Gaultherin
Gaultherin
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Cat. No.: HY-N1965
CAS No.: 490-67-5
Category:  

other families Ketones, Aldehydes, Acids Gaultheria yunnanensis Plants Ericaceae Disease Research Fields Inflammation/Immunology

Target:  

Free Radical Scavengers NF-κB p38 MAPK COX Monoamine Oxidase MMP Interleukin Related TNF Receptor Reactive Oxygen Species (ROS)

Gaultherin is an orally active non-steroidal anti-inflammatory agent. Gaultherin selectively inhibits NF-κB, MAPK, COX-2 (IC50 = 0.35 mg/mL), LOX (IC50 = 0.56 mg/mL) and HYAL (IC50 = 28.58 μg/mL) to exert anti-inflammatory, antipyretic and analgesic effects. Gaultherin exhibits modest direct antioxidant capacity, greater in cell-based models. Gaultherin does not affect COX-1 so that avoids the common gastrointestinal side effects of Aspirin (HY-14654) .
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