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Results for "

MurNAc

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W009274
    N-Acetylmuramic acid

    MurNAc; NAMA

    		 p38 MAPK NF-κB Bacterial Infection Inflammation/Immunology
    N-acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, essential for maintaining cell shape and integrity . N-acetylmuramic acid inhibits spore germination by inhibiting a coat-associated hexosaminidase and a core enzyme . N-acetylmuramic acid is required by Bacteroides forsythus for proliferation and the maintenance of its cell shape . N-Acetylmuramic acid inhibits the p38 MAPK/NF-κB signaling pathway, and exhibits anti-inflammatory activity. N-Acetylmuramic acid is orally active .
    N-Acetylmuramic acid
  • HY-175222
    GlcNAc-MurNAc

    		Toll-like Receptor (TLR) NF-κB Caspase TNF Receptor Interleukin Related Metabolic Disease Inflammation/Immunology
    GlcNAc-MurNAc, a disaccharide, is a TLR4 agonist with a Kd of 383 μM for murine TLR4. GlcNAc-MurNAc directly binds to TLR4 and activates its downstream NF-κB and IRF pathways. GlcNAc-MurNAc improves Dextran sulfate sodium salt (DSS) (HY-116282C)-induced colitis in mice through a TLR4-dependent mechanism. GlcNAc-MurNAc can be used for the study of inflammatory bowel disease .
    GlcNAc-MurNAc
  • HY-166114
    Heptaprenyl-MPDA

    Heptaprenyl phosphate

    		 Biochemical Assay Reagents Infection
    Heptaprenyl-MPDA (Heptaprenyl phosphate) is a short-chain homolog of undecaprenyl phosphate, is an endogenous substrate of Phospho-MurNAc-pentapeptide translocase (MraY). Heptaprenyl-MPDA can be used for bacterial infections research .
    Heptaprenyl-MPDA
  • HY-166114A
    (Z)-Heptaprenyl-MPDA diammonium

    (Z)-Heptaprenyl phosphate diammonium

    		 Bacterial Infection
    (Z)-Heptaprenyl-MPDA ((Z)-Heptaprenyl phosphate) diammonium is the (Z)-isomer of Heptaprenyl-MPDA (HY-166114). Heptaprenyl-MPDA (Heptaprenyl phosphate) is a short-chain homolog of undecaprenyl phosphate, is an endogenous substrate of Phospho-MurNAc-pentapeptide translocase (MraY). Heptaprenyl-MPDA can be used for bacterial infections research .
    (Z)-Heptaprenyl-MPDA diammonium
  • HY-146426
    MraY-IN-2

    		Bacterial Infection
    MraY-IN-2 (compound 6) is a potent MurNAc-pentapeptide translocase (MraY) inhibitor with an IC50 value of 4.5 μM. MraY-IN-2 can be used for researching anti-bacteria .
    MraY-IN-2
  • HY-P11330
    L-Ala-D-Glu-m-DAP-D-Ala-D-Ala

    		Bacterial Infection
    L-Ala-D-Glu-m-DAP-D-Ala-D-Ala is a key structured peptide of peptidoglycan of gram-negative bacteria. Peptidoglycan is a network of L-Ala-D-Glu-m-DAP-D-Ala-D-Ala cross-linking the repeated units of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc). L-Ala-D-Glu-m-DAP-D-Ala-D-Ala can be used for bacterial metabolic labeling research .
    L-Ala-D-Glu-m-DAP-D-Ala-D-Ala

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