2 Results for "

Neplanocin A

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Neplanocin A" in MCE Product Catalog:

Cat. No.: HY-130430
CAS No.: 72877-50-0
Purity:  99.76%
Synonyms: (-)-Neplanocin A
Neplanocin A ((-)-Neplanocin A) is an antitumor antibiotic with significant antitumor activity against murine L1210 leukemia. Neplanocin A is also an irreversible inhibitor of AdoHcy hydrolase (Ki=8.39 nM). Neplanocin A also has antiviral activity and is effective against vaccinia virus. Neplanocin A is obtained from Ampulariella regularis .
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Cat. No.: HY-176059
Target:  

HBV

Research Areas:  

Infection

HBV-IN-52 is a selective HBV inhibitor. HBV-IN-52 is a Neplanocin A (HY-130430) derivative that demonstrates significant activity against HBV replication with EC50 = 0.96 μM. HBV-IN-52 can inhibit HBsAg secretion (EC50 = 0.82 μM. HBV-IN-52 can be studied in research for chronic hepatitis B (CHB) infections .
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