72877-50-0
Chemical Structure
Neplanocin A
Synonym(s): (-)-Neplanocin A
- CAS No.: 72877-50-0
- Formula:C11H13N5O3
- Molecular Weight:263.25
IUPAC Name: (1S,2R,5R)-5-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
InChIKey: XUGWUUDOWNZAGW-VDAHYXPESA-N
SMILES: O[C@@H]1[C@H](O)C(CO)=C[C@H]1N2C=NC3=C(N)N=CN=C23
Biological Activity: Neplanocin A ((-)-Neplanocin A) is an antitumor antibiotic with significant antitumor activity against murine L1210 leukemia. Neplanocin A is also an irreversible inhibitor of AdoHcy hydrolase (Ki=8.39 nM). Neplanocin A also has antiviral activity and is effective against vaccinia virus. Neplanocin A is obtained from Ampulariella regularis[1].
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Neplanocin A | 99.76% | Neplanocin A ((-)-Neplanocin A) is an antitumor antibiotic with significant antitumor activity against murine L1210 leukemia. Neplanocin A is also an irreversible inhibitor of AdoHcy hydrolase (Ki=8.39 nM). Neplanocin A also has antiviral activity and is effective against vaccinia virus. Neplanocin A is obtained from Ampulariella regularis. | ||||||||||||||||||||
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Keywords
