HBV-IN-52
HBV-IN-52 is a selective HBV inhibitor. HBV-IN-52 is a Neplanocin A (HY-130430) derivative that demonstrates significant activity against HBV replication with EC50 = 0.96 μM. HBV-IN-52 can inhibit HBsAg secretion (EC50 = 0.82 μM. HBV-IN-52 can be studied in research for chronic hepatitis B (CHB) infections.
For research use only. We do not sell to patients.
- Formula: C12H13IN4O3
- Molecular Weight:388.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
HBV-IN-25 (Compound 4g) (0-100 μM) shows selective inhibition of HBV DNA replication (EC50 = 0.96 μM) and ability to inhibit HBsAg secretion (EC50 = 0.82 μM) with a CC50 of >100 μM in HepG2.2.15.7cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 388.16
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Formula C12H13IN4O3
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SMILES
OCC1=C[C@@H](N2N=C(I)C3=C2N=CN=C3C)[C@H](O)[C@@H]1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)