10 Results for "

Numidargistat

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "Numidargistat" in MCE Product Catalog:

12
12 Cited Publications
Cat. No.: HY-101979
CAS No.: 2095732-06-0
Purity:  ≥98.0%
Synonyms: CB-1158; INCB01158
Target:  

Arginase

Research Areas:  

Cancer

Numidargistat (CB-1158) is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent .
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12
12 Cited Publications
Cat. No.: HY-101979A
Purity:  98.65%
Synonyms: CB-1158 dihydrochloride; INCB01158 dihydrochloride
Target:  

Arginase

Research Areas:  

Cancer

Numidargistat (CB-1158) dihydrochloride is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent .
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Cat. No.: HY-P11446
CAS No.: 254729-66-3
Research Areas:  

Cancer

AE105 is a 9-mer peptide probe targeting the urokinase-type plasminogen activator receptor (uPAR). AE105 binds tightly to the uPA-binding cavity of uPAR. AE105 can be used for the study of cancer .
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Cat. No.: HY-146127A
Purity:  99.71%
Target:  

Src

Research Areas:  

Others

Grb2 SH2 domain inhibitor 1 TFA is a conformationally restricted cyclic cell penetrating peptide (CPP) containing d-pro-l-pro motif ring (AF Φ Rpprrfq) (where Φ It is L-naphthylalanine, R is D-arginine, P is D-proline), which is mainly used as a cyclic peptide inhibitor.
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Cat. No.: HY-146127
CAS No.: 3069455-54-2
Target:  

MEK

Research Areas:  

Cancer

Grb2 SH2 domain inhibitor 1 is an inhibitor of the Grb2 SH2 domain with an IC50 of 0.40 μM. Grb2 SH2 domain inhibitor 1 is also a cell-permeable cyclic peptide that can enter the cytosol of mammalian cells. Grb2 SH2 domain inhibitor 1 downregulates the expression level of p-MEK. Grb2 SH2 domain inhibitor 1 can be used in the research of breast cancer .
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Cat. No.: HY-P10304C
CAS No.: 181961-24-0
Target:  

Fungal

Research Areas:  

Infection

Cyclo(Pro-dArg) is an inhibitor of chitinase. Cyclo(Pro-dArg) inhibits the cell separation of Saccharomyces cerevisiae but does not affect its growth. Cyclo(Pro-dArg) inhibits the transition of Candida albicans from yeast to filamentous morphology.
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Cat. No.: HY-P11446A
Research Areas:  

Cancer

AE105 TFA is a 9-mer peptide probe targeting the urokinase-type plasminogen activator receptor (uPAR). AE105 TFA binds tightly to the uPA-binding cavity of uPAR. AE105 TFA can be used for the study of cancer .
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Cat. No.: HY-101979R
CAS No.: 2095732-06-0
Synonyms: CB-1158 (Standard); INCB01158 (Standard)
Research Areas:  

Cancer

Numidargistat (Standard) is the analytical standard of Numidargistat (HY-101979). This product is intended for research and analytical applications. Numidargistat (CB-1158) is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent .
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Cat. No.: HY-P10304D
Target:  

Fungal

Research Areas:  

Infection

Cyclo(Pro-dArg) acetate is a chitinase inhibitor. Cyclo(Pro-dArg) acetate inhibits the cell separation of Saccharomyces cerevisiae but does not affect its growth. Cyclo(Pro-dArg) acetate inhibits the transition of Candida albicans from yeast to filamentous morphology .
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Cat. No.: HY-P11807
Target:  

ADC Linkers

Research Areas:  

Cancer

DArg-DLys-DTyr-DTyr-Gly-DTrp is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) .
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