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Cat. No.: HY-P11807

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DArg-DLys-DTyr-DTyr-Gly-DTrp

DArg-DLys-DTyr-DTyr-Gly-DTrp is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Formula: C₄₃H₅₇N₁₁O₉
Molecular Weight:871.98

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Custom Peptide Synthesis

DArg-DLys-DTyr-DTyr-Gly-DTrp Chemical Structure

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Use of MCE Products

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

DArg-DLys-DTyr-DTyr-Gly-DTrp is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

ADC linker

All ADC Linkers Isoforms :

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 871.98
Formula C₄₃H₅₇N₁₁O₉
Sequence

DArg-DLys-DTyr-DTyr-Gly-DTrp
Sequence Shortening

DArg-DLys-DTyr-DTyr-G-DTrp
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Li MJ, et al. Transcending stereochemical boundaries: ambidextrous cleavage of d- and l-peptide enantiomers by natural eukaryotic proteases. Vita. 2026 Apr 20.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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DArg-DLys-DTyr-DTyr-Gly-DTrp

All ADC Linkers Isoforms