10 Results for "

Orphan GPCR receptor

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "Orphan GPCR receptor" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-113962
CAS No.: 64907-22-8
Purity:  99.88%
Synonyms: 7α,25-OHC
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells .
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Cat. No.: HY-N15721
CAS No.: 1630745-39-9
Synonyms: Trp-CA
Tryptophan-cholic acid (Trp-CA) is a microbial amino acid-conjugated bile acid that acts as an endogenous ligand and agonist (EC50=9.6 μM) for the orphan G protein-coupled receptor (GPCR) MRGPRE (Mas-related G protein-coupled receptor family member E). Tryptophan-cholic acid is orally effective but has poor oral absorption and does not cross the blood-brain barrier. Tryptophan-cholic acid promotes the secretion of glucagon-like peptide GLP-1, thereby improving glucose tolerance in diabetic mice. Tryptophan-cholic acid improves glucose tolerance, promotes insulin secretion, and alleviates high-fat diet-induced hepatic steatosis without causing pruritus side effects. Tryptophan-cholic acid is primarily used in research on type 2 diabetes (T2D) .
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Cat. No.: HY-113962S
CAS No.: 2260669-11-0
Synonyms: 7α,25-OHC-d6
7α,25-Dihydroxycholesterol-d6 is deuterium labeled 7α,25-Dihydroxycholesterol. 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly
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Cat. No.: HY-400897
CAS No.: 1326612-12-7
Research Areas:  

Cancer

7α,25-Dihydroxycholesterol intermediate-1 is an intermediate in the synthesis of 7α,25-Dihydroxycholesterol (HY-113962). 7α,25-Dihydroxycholesterol (7α,25-OHC) can be used as a ligand to target the orphan GPCR receptor EBI2 (GPR183). body, used to synthesize the corresponding PROTEACs .
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Cat. No.: HY-P10289A
Synonyms: NPW30, rat acetate
Research Areas:  

Neurological Disease

Neuropeptide W-30 (rat) is an important stress mediator in the central nervous system that modulates the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. Neuropeptide W-30 (rat) is an endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8. NPW-30 activates and binds to both GPR7 and GPR8 at similar effective doses .
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Cat. No.: HY-P10287
CAS No.: 383415-80-3
Synonyms: NPW30, human
Research Areas:  

Neurological Disease

Neuropeptide W-30 (human) is an important stress mediator in the central nervous system that modulates the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. Neuropeptide W-30 (human) is an endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8. Neuropeptide W-30 (human) activates and binds to both GPR7 and GPR8 at similar effective doses .
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Cat. No.: HY-P2472
CAS No.: 600171-70-8
Synonyms: 26RFa (mouse, rat)
Research Areas:  

Metabolic Disease

Orphan GPCR SP9155 agonist P550 (mouse, rat) (26RFa (mouse, rat)), a member of the RFamide peptide family with orexigenic effect, is the cognate ligand of the mouse orphan receptor GPR103, also designated SP9155 or AQ27 .
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Cat. No.: HY-P5084
CAS No.: 1138204-27-9
Neuromedin S (human) is a neuropeptide that contains 33 amino acids. Neuromedin S (human)has been identified in the brain as an endogenous ligand for the orphan G-protein coupled receptor (GPCR) FM-4/TGR-1 and acts on the neuromedin U (NMU) receptor 2 (NMUR2) in the regulation of body weight homeostasis .
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Cat. No.: HY-P10289
CAS No.: 383415-90-5
Synonyms: NPW30, rat
Research Areas:  

Neurological Disease

Neuropeptide W-30 (rat) is an important stress mediator in the central nervous system that modulates the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. Neuropeptide W-30 (rat) is an endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8. NPW-30 activates and binds to both GPR7 and GPR8 at similar effective doses .
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Cat. No.: HY-P704229
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: GPR87; G-Protein Coupled receptor 95; Prev. GPR95; KPG_002; G-Protein Coupled receptor 87; FKSG78; G Protein-Coupled receptor 87; Orphan GPCR 87
Species:  
Source:  
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