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PKR2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Prokineticin Receptor (3) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (2) Inflammation/Immunology (2) Neurological Disease (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (2) siRNAs (2)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Targets Recommended: PERK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-147056

PKRA83 PKRA7	Prokineticin Receptor	Neurological Disease Inflammation/Immunology Cancer
PKRA83 (PKRA7) is a potent prokineticin (PK2) antagonist, which can compete for the binding of PK2 to its receptors PKR1 and PKR2. PKRA83 potently inhibits PK2 receptors, with IC₅₀ values of 5.0 nM and 8.2 nM for PKR1 and PKR2, respectively. PKRA83 has anticancer, anti-arthritis and anti-angiogenic activities. ^[2] .

HY-129317

A457	Prokineticin Receptor	Others
A457 is a prokineticin receptor PKR2 antagonist, with an IC₅₀ of 102 nM. A457 can rescue the cell surface expression and function of P290S PKR2, but not W178S and G234D PKR2 .

HY-147056B

PKRA83 hydrochloride PKRA7 hydrochloride	Prokineticin Receptor	Inflammation/Immunology Cancer
PKRA83 (PKRA7) hydrochloride is a potent PK2 antagonist that competes for PK2 binding to its receptors, PKR1 and PKR2. PKRA83 hydrochloride potently inhibits PK2 receptors with IC₅₀ values of 5.0 nM and 8.2 nM for PKR1 and PKR2, respectively. PKRA83 hydrochloride exhibits anticancer, antiarthritis, and antiangiogenic activities .

HY-RS11114

PRKAR2A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PRKAR2A Human Pre-designed siRNA Set A contains three designed siRNAs for PRKAR2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PRKAR2A Human Pre-designed siRNA Set A PRKAR2A Human Pre-designed siRNA Set A

HY-RS11197

PROKR2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PROKR2 Human Pre-designed siRNA Set A contains three designed siRNAs for PROKR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PROKR2 Human Pre-designed siRNA Set A PROKR2 Human Pre-designed siRNA Set A

Host:	Mouse (1) Rabbit (2)
Reactivity:	Human (2) mouse (1) Rat (1) Mouse (1) rat (1) human (1) Pig (1)
Application:	IHC-P (2) ICC/IF (2) IF-Tissue (1) IP (3) WB (3) ELISA (1)
Isotype:	IgG (2) IgG1 (1)
Conjugation:	Non-conjugated (3)
Clonality:	Polyclonal (1) Monoclonal (1) Recombinant (1)
Modification:	Phosphorylated (1) Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P89787

	PKR2 Antibody (YA9131)	WB, ICC/IF, IF-Tissue, IP, ELISA	human, mouse, rat
	PKR2 Antibody (YA9131) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PKR2.

HY-P80847

	*Phospho-PKA R2/PKR2* (Ser99) Antibody** 2 Publications Verification PRKAR2A; PKR2; PRKAR2; cAMP-dependent protein kinase type II-alpha regulatory subunit	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat, Pig
	Phospho-PKA R2/PKR2 (Ser99) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-PKA R2/PKR2 (Ser99).

HY-P80429

	*PKA R2/PKR2* Antibody (YA132)**	WB, IHC-P, IP	Human
	PKA R2/PKR2 Antibody (YA132) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PKA R2/PKR2.

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PRKAR2A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PRKAR2A Human Pre-designed siRNA Set A contains three designed siRNAs for PRKAR2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PROKR2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PROKR2 Human Pre-designed siRNA Set A contains three designed siRNAs for PROKR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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