Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
PW0464
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "PW0464" in MCE Product Catalog:
1
Target:
Research Areas:
PW0464, a nanomolar potent complete G protein biased ligand, is a noncatechol D1R agonist, with an EC50 of 5.8 nM (Gs-cAMP) .
Cat. No.: HY-141495A
CAS No.: 1643489-35-3
Synonyms: (-)-PW0464
Target:
Research Areas:
Razpipadon ((-)-PW0464) is an isomer of (Rac)-Razpipadon (HY-141495).
Cat. No.: HY-141495B
CAS No.: 1643489-51-3
Synonyms: (+)-PW0464
Target:
Research Areas:
(+)-Razpipadon ((+)-PW0464) is a selective D1 dopamine receptor agonist belonging to non-catechol compounds. (+)-Razpipadon activates the G protein pathway, while restricting β-arrestin coupling through the proximity effect of fluoromethyl-TM5, thereby achieving specific regulation of downstream pathways. (+)-Razpipadon can be used in studies related to Parkinson's disease .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
