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Picrasidine A

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N3071

    Apoptosis Reactive Oxygen Species (ROS) Inflammation/Immunology
    Picrasidine I is an anti-inflammatory and anti-osteoclastogenic dimeric alkaloid that can be isolated from Picrasma quassioides. Picrasidine I inducs cell cycle arrest, and triggers cell apoptosis by downregulats ERK and Akt pathways. Picrasidine I inhibits the activation of MAPKs, NF-κB and ROS generation, and suppresses the expression of c-Fos and NFATc1 .
    Picrasidine I
  • HY-N9507

    Apoptosis FGFR Cancer
    Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits FGFR2 kinase activity .
    Picrasidine Q
  • HY-113757

    Others Others
    Picrasidine M (compound II) is an alkaloid that can be isolated from the root bark of Picrasma quassinoids BENNET .
    Picrasidine M
  • HY-N16720

    Reactive Oxygen Species (ROS) Inflammation/Immunology
    Picrasidine A is an active compound that can be extracted from the natural product Picrasma quassioides (D. Don) Benn. Picrasidine A has the potential to prevent UVB-induced reactive oxygen species (ROS) generation .
    Picrasidine A
  • HY-N16719

    Kallikrein ERK Cadherin β-catenin Cancer
    Picrasidine J is a selective inhibitor targeting the KLK-10 protease and the ERK signaling pathway. Picrasidine J inhibits epithelial-mesenchymal transition (EMT) by upregulating E-Cadherin and ZO-1 and downregulating β-catenin and Snail, while simultaneously reducing KLK-10 expression and inhibiting ERK phosphorylation, thereby exhibiting significant anti-migratory and anti-invasive activity. Picrasidine J can inhibit the metastasis of head and neck squamous cell carcinoma (HNSCC) and is primarily used in anti-metastasis research for head and neck tumors .
    Picrasidine J

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