9 Results for "

Pimelic Acid

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Pimelic Acid" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-Y1139
CAS No.: 111-16-0
Synonyms: Heptanedioic Acid; 1,5-Pentanedicarboxylic Acid; 1,7-Heptanedioic Acid
Pimelic acid (Heptanedioic acid; 1,5-Pentanedicarboxylic acid) is a seven-carbon α,ω-dicarboxylic acid and a downstream product of fatty acid synthesis. Pimelic acid is a key precursor in biotin biosynthesis. Pimelic acid can be converted to pimelic acid-CoA by the BioW enzyme, thereby bypassing exogenous biotin requirements to support growth in various biotinytrophic bacteria and fungi, and reversing antibiotic-induced inhibition of biotin synthesis. Furthermore, Pimelic acid has been proposed as a highly specific biomarker for oxygen-induced retinopathy in mice. Pimelic acid can be used to study retinopathy of preterm infants, oxygen-induced retinopathy, and microbial biotin metabolism .
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5
5 Cited Publications
Cat. No.: HY-19348
CAS No.: 937039-45-7
Synonyms: RGFA-8; TC-H 106; Histone Deacetylase Inhibitor VII
Research Areas:  

Neurological Disease Cancer

Pimelic Diphenylamide 106 (TC-H 106) is a slow, tight binding class I HDAC inhibitor (inhibits HDAC1, 2, and 3 with IC50 values of 150 nM, 760 nM, and 370 nM, respectively), with no activity against class II HDACs. Pimelic Diphenylamide 106 modulates dopamine concentration and protects dopamine cells by inducing VMAT2 expression. Pimelic Diphenylamide 106 can be used in the study of neuropsychiatric diseases such as attention deficit hyperactivity disorder (ADHD) .
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2
2 Cited Publications
Cat. No.: HY-19430
CAS No.: 2070015-24-4
Synonyms: RGFA-8 analog; TC-H 106 analog
Target:  

HDAC

Research Areas:  

Cancer

Pimelic Diphenylamide 106 analog is the analog of Pimelic Diphenylamide 106, with unknown activity.
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Cat. No.: HY-W041806
CAS No.: 3710-42-7
Target:  

Drug Intermediate

Research Areas:  

Others

7-Hydroxyheptanoic acid is an intermediate. 7-Hydroxyheptanoic acid can be dehydrolyzed to Pimelic acid (HY-Y1139). Pimelic acid derivatives can participate in the biosynthesis of lysine .
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Cat. No.: HY-W001472
CAS No.: 1732-08-7
Synonyms: Pimelic Acid dimethyl ester
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

Dimethyl pimelate (Pimelic acid dimethyl ester) is an ester product.
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Cat. No.: HY-176430
CAS No.: 2353496-83-8
Research Areas:  

Cancer

Lenalidomide-amide-pimelic acid is an E3 ligase ligand-linker conjugate that incorporates the Lenalidomide (HY-A0003) based CRBN ligand and Linker (HY-Y1139). Lenalidomide-amide-pimelic acid can be used for synthesis of PROTAC MNK1 degrader-1 (HY-176428) .
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Cat. No.: HY-Y1139R
CAS No.: 111-16-0
Synonyms: Heptanedioic Acid (Standard); 1,5-Pentanedicarboxylic Acid (Standard); 1,7-Heptanedioic Acid (Standard)
Pimelic acid (Standard) is the analytical standard of Pimelic acid. This product is intended for research and analytical applications. Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.Pimelic acid can be used in keratoconus research .
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Cat. No.: HY-Y1139S
CAS No.: 19031-56-2
Synonyms: Heptanedioic Acid-d4; 1,5-Pentanedicarboxylic Acid-d4; 1,7-Heptanedioic Acid-d4
Pimelic acid-d4 is the deuterium labeled Pimelic acid . Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.
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Cat. No.: HY-W001472S
CAS No.: 120811-82-7
Synonyms: Pimelic Acid Dimethyl Ester-d4
Dimethyl pimelate-d4 is the deuterium labeled Dimethyl pimelate .
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