Pimelic Diphenylamide 106 analog
Based on 2 publication(s) in Google Scholar
Pimelic Diphenylamide 106 analog is the analog of Pimelic Diphenylamide 106, with unknown activity.
For research use only. We do not sell to patients.
- Purity: 96.06%
- CAS No.: 2070015-24-4
- Formula: C21H27N3O2
- Molecular Weight:353.46
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Pimelic Diphenylamide 106 analog
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Biological Activity
Chemical Information
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CAS No. 2070015-24-4
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Appearance Solid
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Molecular Weight 353.46
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Formula C21H27N3O2
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Color White to off-white
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SMILES
O=C(NC1=CC=CC=C1N)CCCCCCC(NC2=CC=C(C)C=C2)=O
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Synonyms
RGFA-8 analog; TC-H 106 analog
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (2)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : ≥ 30 mg/mL (84.88 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Chou CJ, et al. Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases. J Biol Chem. 2008 Dec 19;283(51):35402-35409. [Content Brief]
[2]. Xu C, et al. Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing. Chem Biol. 2009 Sep 25;16(9):980-989. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8292 mL | 14.1459 mL | 28.2917 mL | 70.7294 mL |
| 5 mM | 0.5658 mL | 2.8292 mL | 5.6583 mL | 14.1459 mL | |
| 10 mM | 0.2829 mL | 1.4146 mL | 2.8292 mL | 7.0729 mL | |
| 15 mM | 0.1886 mL | 0.9431 mL | 1.8861 mL | 4.7153 mL | |
| 20 mM | 0.1415 mL | 0.7073 mL | 1.4146 mL | 3.5365 mL | |
| 25 mM | 0.1132 mL | 0.5658 mL | 1.1317 mL | 2.8292 mL | |
| 30 mM | 0.0943 mL | 0.4715 mL | 0.9431 mL | 2.3576 mL | |
| 40 mM | 0.0707 mL | 0.3536 mL | 0.7073 mL | 1.7682 mL | |
| 50 mM | 0.0566 mL | 0.2829 mL | 0.5658 mL | 1.4146 mL | |
| 60 mM | 0.0472 mL | 0.2358 mL | 0.4715 mL | 1.1788 mL | |
| 80 mM | 0.0354 mL | 0.1768 mL | 0.3536 mL | 0.8841 mL |
Pimelic Diphenylamide 106 analog Related Classifications
HY-19430 Related Classifications
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