6 Results for "

Piperlongumine

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Piperlongumine" in MCE Product Catalog:

16
16 Cited Publications
Cat. No.: HY-N2329
CAS No.: 20069-09-4
Synonyms: Piplartine
Piperlongumine is a alkaloid , possesses ant-inflammatory, antibacterial, antiangiogenic, antioxidant, antitumor, and antidiabetic activities . Piperlongumine induces ROS, and induces apoptosis in cancer cell lines . Piperlongumine shows anti-cardiac fibrosis activity, suppresses myofibroblast transformation via suppression of the ERK1/2 signaling pathway. Piperlongumin could be used in the study of migrasome .
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1
1 Cited Publications
Cat. No.: HY-147803
Purity:  98.07%
Research Areas:  

Cancer

TrxR-IN-5 (compound 4f) is a potent TrxR (thioredoxin reductase) inhibitor, with an IC50 of 0.16 μM. TrxR-IN-5 increases the levels of ROS, thus leading to potent antiproliferative effects. TrxR-IN-5 exhibits prominent anticacer and anti-metastasis effects .
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Cat. No.: HY-161088
CAS No.: 1884611-28-2
Target:  

Drug Derivative ERK

Research Areas:  

Others

Anti-aging agent 1 (compound 24) is a derivative of piperlongumine (HY-N2329) (PL). Anti-aging agent 1 exhibits a 50-fold enhancement in senolytic activity against senescent WI-38 fibroblasts compared to PL .
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Cat. No.: HY-N2329R
CAS No.: 20069-09-4
Synonyms: Piplartine (Standard)
Piperlongumine is a alkaloid , possesses ant-inflammatory, antibacterial, antiangiogenic, antioxidant, antitumor, and antidiabetic activities . Piperlongumine induces ROS, and induces apoptosis in cancer cell lines . Piperlongumine shows anti-cardiac fibrosis activity, suppresses myofibroblast transformation via suppression of the ERK1/2 signaling pathway. Piperlongumin could be used in the study of migrasome .
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Cat. No.: HY-163451
CAS No.: 3126845-21-1
Target:  

Apoptosis

Research Areas:  

Cancer

Apoptosis inducer 17 is a Curcumin-Piperlongumine hybrid molecule that increases cell cycle arrest and apoptosis through activating JNK signaling pathway in lung cancer cells .
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Cat. No.: HY-145413
CAS No.: 1415153-39-7
Research Areas:  

Cancer

BRD2889 is an analog of the alkaloid piperlongumine. BRD2889 is a robust modulator of the GSTP1-ISCU axis in pulmonary hypertension (PH) . BRD2889 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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