13 Results for "

Praeruptorin A

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "Praeruptorin A" in MCE Product Catalog:

Cat. No.: HY-N0081
CAS No.: 73069-25-7
(±)-Praeruptorin A, a coumarin compound, is the main bioactive component in Peucedani Radix. As a calcium channel blocker, (±)-Praeruptorin A exhibits great antihypertensive effects. In addition, (±)-Praeruptorin A also has the effects of relaxing vascular smooth muscle, inhibiting airway inflammation and airway hyperresponsiveness. (±)-Praeruptorin A can be used for the research of allergic asthma, hypertension and other diseases .
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3 Cited Publications
Cat. No.: HY-N6065
CAS No.: 73069-27-9
Synonyms: (+)-Praeruptorin A
Praeruptorin A ((+)-Praeruptorin A) is an orally active isomer of (±)-Praeruptorin A (HY-N0081). Praeruptorin A also acts as a Calcium channel blocker. Praeruptorin A can be isolated from Peucedanum. Praeruptorin A serves as a substrate for CYP3A4. Praeruptorin A downregulates NMDA receptors containing GluN2B and inhibits neuronal Apoptosis. Praeruptorin A mediates vasodilation, inhibits vascular hypertrophy and reduces blood pressure. Praeruptorin A can be used in research related to neurological diseases, myocardial ischemia, heart failure, exertional angina, renovascular hypertension and spontaneous hypertension .
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Cat. No.: HY-N0081A
CAS No.: 14017-71-1
(-)-Praeruptorin A is a nature product that could be isolated from the roots of Peucedanum praeruptorum Dunn. (-)-Praeruptorin A relaxes ileum and tracheal smooth muscles by activating NO/cGMP signaling pathway. (-)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca 2+-influx blocker .
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1 Cited Publications
Cat. No.: HY-N0079
CAS No.: 72463-77-5
Praeruptorin C is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin C is a calcium antagonist with pD2 value of 5.7 .
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Cat. No.: HY-N6066
CAS No.: 78478-28-1
Praeruptorin E is an orally active pyranocoumarin compound. Praeruptorin E can be isolated from the dried roots of Peucedanum praeruptorum Dunn. Praeruptorin E reduces the expression of NF-κB. Praeruptorin E upregulates the expression of PXR and CYP3A4. Praeruptorin E inhibits Th2 cytokines, TNF-α, IL6, MPO, and blocks the Ca 2+ slow channel. Praeruptorin E promotes pulmonary tissue repair and relaxes porcine coronary artery strips. Praeruptorin E protects mice from lipopolysaccharide- and hydrochloric acid-induced acute lung injury. Praeruptorin E can be used in studies related to asthma and acute lung injury .
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Cat. No.: HY-N0082
CAS No.: 73069-28-0
Synonyms: Praeruptorin D
Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs).
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Cat. No.: HY-N0947
CAS No.: 4970-26-7
Synonyms: (-)-Praeruptorin B
(-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .
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Cat. No.: HY-N6065R
CAS No.: 73069-27-9
Synonyms: (+)-Praeruptorin A (Standard)
Praeruptorin A (Standard) is the analytical standard of Praeruptorin A. This product is intended for research and analytical applications. Praeruptorin A is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation .
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Cat. No.: HY-N0081R
CAS No.: 73069-25-7
(±)-Praeruptorin A (Standard) is the analytical standard of (±)-Praeruptorin A (HY-N0081). This product is intended for research and analytical applications. (±)-Praeruptorin A, a coumarin compound, is the main bioactive component in Peucedani Radix. As a calcium channel blocker, (±)-Praeruptorin A exhibits great antihypertensive effects. In addition, (±)-Praeruptorin A also has the effects of relaxing vascular smooth muscle, inhibiting airway inflammation and airway hyperresponsiveness. (±)-Praeruptorin A can be used for the research of allergic asthma, hypertension and other diseases .
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Cat. No.: HY-N0082R
CAS No.: 73069-28-0
Synonyms: Praeruptorin D (Standard)
Praeruptorin B (Standard) is the analytical standard of Praeruptorin B. This product is intended for research and analytical applications. Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs).
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Cat. No.: HY-N6066R
CAS No.: 78478-28-1
Praeruptorin E (Standard) is the analytical standard of Praeruptorin E. This product is intended for research and analytical applications. Praeruptorin E is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin C is a calcium antagonist with pD2′ value of 5.2 .
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Cat. No.: HY-N0947R
CAS No.: 4970-26-7
Synonyms: (-)-Praeruptorin B (Standard)
(-)-Anomalin (Standard) is the analytical standard of (-)-Anomalin. This product is intended for research and analytical applications. (-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .
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Cat. No.: HY-N17350
CAS No.: 1422965-31-8
Praeruptorin H is a natural product that can be found in white flower peucedanum.
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