12 Results for "

SEVNLDAEFR

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "SEVNLDAEFR" in MCE Product Catalog:

Cat. No.: HY-P2714
CAS No.: 186142-28-9
Target:  

Beta-secretase

Research Areas:  

Neurological Disease

SEVNLDAEFR is a substrate for BACE1 .
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Cat. No.: HY-P1859
CAS No.: 438625-61-7
Target:  

Fluorescent Dye

Research Areas:  

Others

MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.
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Cat. No.: HY-P5905
Synonyms: Citrullinated Aβ (1-42); Citrullinated Aβ42
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Citrullinated amyloid-β (1-42) peptide (human) (Citrullinated Aβ (1-42)) is a modified form of β-Amyloid (1-42) (HY-P1363) with a citrullination at the Arg5 site. Compared to the unmodified β-Amyloid (1-42), its formation of soluble low-molecular-weight oligomers is enhanced, the rate of fibril formation is reduced, and like unmodified Aβ42, it forms protofibrils comprised of parallel β-sheets .
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Cat. No.: HY-P4920
CAS No.: 1802078-32-5
Target:  

Fluorescent Dye

Research Areas:  

Others

Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1 .
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Cat. No.: HY-P1859A
Research Areas:  

Others

MCA-SEVNLDAEFR-K(Dnp)-RR, amide (acetate) is synthesized from MCA-SEVNLDAEFR-K(Dnp)-RR, amide (HY-P1859) by losing the H of the -OH group of acetic acid. MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.
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Cat. No.: HY-P5906
Synonyms: Citrullinated Aβ (1-40); Citrullinated Aβ40
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Citrullinated amyloid-β (1-40) peptide (human) (Citrullinated Aβ (1-40)) is a modified form of β-Amyloid (1-40) (HY-P0265) with a citrullination at the Arg5 site. Citrullinated amyloid-β (1-40) peptide (human) exhibits increased transient formation of soluble oligomers and insoluble aggregates composed of distorted parallel β-sheets compared with unmodified β-Amyloid (1-40) .
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Cat. No.: HY-P10196
CAS No.: 1802078-36-9
Target:  

Peptides

Research Areas:  

Others

DABCYL-SEVNLDAEF-EDANS is a substrate of FRET. DABCYL-SEVNLDAEF-EDANS can be used in the BACE activity assay .
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Cat. No.: HY-P4940
CAS No.: 1007306-20-8
Target:  

Peptides

Research Areas:  

Others

Abz-Val-Asn-Leu-Asp-Ala-Glu-EDDnp is a quenched fluorometric substrate .
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Cat. No.: HY-P1729
CAS No.: 310427-95-3
Target:  

Fluorescent Dye

Research Areas:  

Neurological Disease

M-2420 is a fluorogenic substrate containing β-secretase site of the Swedish mutation of amyloid precursor protein (APP) .
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Cat. No.: HY-P4919
CAS No.: 1802078-31-4
Target:  

Beta-secretase

Research Areas:  

Others

Mca-SEVNLDAEFK(Dnp) is a Beta-secretase 1 (BACE-1) peptide FRET substrate, containing the 'Swedish' Lys-Met/Asn-Leu mutation of the amyloid precursor protein (APP) β-secretase cleavage site. Cleavage at -Leu-Asp- of Mca-SEVNLDAEFK(Dnp) liberates the highly fluorescent 7-methoxycoumarin (Mca) fragment from the proximity quenching effect of the 2,4-dinitrophenyl (Dnp) internal quencher resulting in a large and easily detectable increase in fluorescence intensity.
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Cat. No.: HY-P4899
CAS No.: 310427-94-2
Synonyms: RE(EDANS)EVNLDAEFK(DABCYL)R
Target:  

Beta-secretase

Research Areas:  

Neurological Disease

β-Secretase substrate VI, fluorogenic is an EDANS and DABCYL double-labeled peptide,serves as a fluorescent substrate for BACE1(Em=360nm,Ex=528nm). β-Secretase substrate VI, fluorogenic can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction .
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Cat. No.: HY-P10197
CAS No.: 1802078-37-0
Target:  

Peptides

Research Areas:  

Others

DABCYL-VNLDAE-EDANS is a substrate of b-secretase. DABCYL-VNLDAE-EDANS can be used in BACE enzyme assays .
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