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Results for "

SF 2312

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117778
    SF2312

    		Enolase Bacterial Antibiotic Infection Cancer
    SF2312, a natural phosphonate antibiotic (Antibiotic), is a highly potent Enolase inhibitor with IC50s of 37.9 nM and 42.5 nM for human recombinant ENO1 and ENO2, respectively. SF2312 is active against bacteria under anaerobic conditions .
    SF2312
  • HY-117778B
    SF2312 ammonium

    		Enolase Bacterial Antibiotic ATP Synthase Infection Cancer
    SF2312 ammonium is a phosphonate Antibiotic and Enolase inhibitor, with an IC50 of 18.4 nM against E. coli enolase. SF2312 ammonium reduces intracellular ATP levels and inhibits glycolytic flux. SF2312 ammonium exhibits activity against both Gram-positive and Gram-negative bacteria, and exerts synergistic effects against E. coli when combined with Fosfomycin (HY-B1075A). SF2312 ammonium shows selective toxicity toward gliomas with ENO1 gene knockout. SF2312 ammonium can be used in research related to bacterial infections and gliomas .
    SF2312 ammonium

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