2 Results for "

SIRT7 cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "SIRT7 cells" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N0912
CAS No.: 81720-08-3
Rehmannioside D is an orally active Sirt7 modulator. Rehmannioside D upregulates Sirt7 expression, inhibits the level of acetylated p53, and blocks the activation of the p53 signaling pathway. Rehmannioside D alleviates liver injury, inflammatory response, collagen deposition and hepatocyte apoptosis. Rehmannioside D is applicable to research related to liver fibrosis .
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Cat. No.: HY-159124
CAS No.: 3031072-69-9
Target:  

Sirtuin

Research Areas:  

Cancer

YZL-51N is a selective SIRT7 inhibitor with IC50 value of 12.71 μM. YZL-51N disrupts SIRT7 enzyme activity by occupying the NAD + binding pocket, thereby weakening DNA damage repair and inhibiting cancer cell survival. YZL-51N possesses anti-tumor activity and can be used in cancer research .
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