3031072-69-9
3031072-69-9
Chemical Structure
YZL-51N
- CAS No.: 3031072-69-9
- Formula:C17H14O7
- Molecular Weight:330.29
InChIKey: HZWOUVYWQBKNFS-FLIBITNWSA-N
SMILES: O=C(OC)/C(C1=CC=C(O)C(O)=C1)=C\C(C2=CC=C(O)C(O)=C2)=O
Biological Activity: YZL-51N is a selective SIRT7 inhibitor with IC50 value of 12.71 μM. YZL-51N disrupts SIRT7 enzyme activity by occupying the NAD+ binding pocket, thereby weakening DNA damage repair and inhibiting cancer cell survival. YZL-51N possesses anti-tumor activity and can be used in cancer research[1].
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YZL-51N | 95.0% | YZL-51N is a selective SIRT7 inhibitor with IC50 value of 12.71 μM. YZL-51N disrupts SIRT7 enzyme activity by occupying the NAD+ binding pocket, thereby weakening DNA damage repair and inhibiting cancer cell survival. YZL-51N possesses anti-tumor activity and can be used in cancer research. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.70
HY-N9334Tetrahydroxymethoxychalcone -
Similarity Score 0.70
HY-135436AG 538 -
Similarity Score 0.66
HY-150156Anti-inflammatory agent 32 -
Similarity Score 0.66
HY-N11766Calythropsin -
Similarity Score 0.66
HY-N8263Nepetoidin B -
Similarity Score 0.66
HY-16558Butein -
Similarity Score 0.65
HY-N6673Okanin -
Similarity Score 0.65
HY-59001Sappanchalcone -
Similarity Score 0.64
HY-N9551Eriodictyol chalcone -
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