4 Results for "

SPI-2

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "SPI-2" in MCE Product Catalog:

Cat. No.: HY-P71302
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Serine protease inhibitor A3N; Serpin A3N; Serpina3n; SPI2
Species:  
Source:  
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Cat. No.: HY-P71841
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Serine protease inhibitor A3N; Serpin A3N; Serpina3n; SPI2
Species:  
Source:  
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Cat. No.: HY-P74558
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: Serine protease inhibitor A3N; Serpin A3N; Serpina3n; SPI2
Species:  
Rat
Source:  
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Cat. No.: HY-182305
CAS No.: 2411865-57-9
Target:  

Bacterial

Research Areas:  

Infection

VKT-17-P4-23 is a blood-brain barrier-permeable DksA inhibitor. DksA is a highly conserved transcriptional regulator in Gram-negative bacteria, with a Kd of 124 μM. Through the DksA-regulated, SPI-2-dependent survival pathway, VKT-17-P4-23 exhibits antibacterial activity against both planktonic and intracellular pathogens such as Salmonella, and also effectively combats persistent bacteria that are difficult to eliminate. VKT-17-P4-23 can be used in studies of Salmonella infection .
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