5 Results for "

SR 1

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "SR 1" in MCE Product Catalog:

18
18 Cited Publications
Cat. No.: HY-15001
CAS No.: 1227633-49-9
Purity:  99.95%
Synonyms: SR1
Research Areas:  

Cancer

Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with IC50 of 127 nM.
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Cat. No.: HY-15001G
CAS No.: 1227633-49-9
Synonyms: SR1 (GMP)
Stemregenin 1 (SR1) (GMP) is a GMP-grade Stemregenin 1 (HY-15001). GMP-grade small molecules can be used as adjuvants in cell therapy. Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with an IC50 of 127 nM. Stemregenin 1 (GMP) can competitively bind to AhR and inhibit its nuclear translocation, inhibiting osteoclastogenesis and promoting hematopoietic progenitor cell expansion by blocking the AhR-c-src-NF-κB/p-ERK MAPK-NFATc1 signaling pathway. Stemregenin 1 (GMP) can be used for the study of osteoporosis, in vitro expansion of hematopoietic stem cells, and the study of the mechanism of bone metabolic diseases .
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Cat. No.: HY-P990851

Target:  

c-Kit

Research Areas:  

Inflammation/Immunology Cancer

Anti-c-Kit/CD117 Antibody (SR-1) is a kind of mouse IgG2a κ chimeric antibody inhibitor, targeting to human c-Kit/CD117. Anti-c-Kit/CD117 Antibody (SR-1) binds to the extracellular domain of human c-Kit (also known as CD117) and blocks stem cell factor (SCF) binding to CD117. Anti-c-Kit/CD117 Antibody (SR-1) can be used for the researches of cancer and immunology, such as gastrointestinal stromal tumor (GIST) and xenograft .
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Cat. No.: HY-15001R
CAS No.: 1227633-49-9
Synonyms: SR1 (Standard)
Research Areas:  

Cancer

Stemregenin 1 (Standard) is the analytical standard of Stemregenin 1. This product is intended for research and analytical applications. Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with IC50 of 127 nM.
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Cat. No.: HY-15001A
CAS No.: 2319882-01-2
Synonyms: SR1 hydrochloride
Research Areas:  

Others

Stemregenin 1 hydrochloride is a purine derivative that antagonizes aryl hydrocarbon receptor signaling in CD34+ cells. IC50 The value is 127 nM. Stemregenin 1 hydrochloride can be used to expand the pluripotency of hematopoietic stem cells (HSC) in stem cell studies .
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