2. Immunology/Inflammation
  3. Aryl Hydrocarbon Receptor
  4. Stemregenin 1 hydrochloride

Stemregenin 1 hydrochloride  (Synonyms: SR1 hydrochloride)

Cat. No.: HY-15001A
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Stemregenin 1 hydrochloride is a purine derivative that antagonizes aryl hydrocarbon receptor signaling in CD34+ cells. IC50 The value is 127 nM. Stemregenin 1 hydrochloride can be used to expand the pluripotency of hematopoietic stem cells (HSC) in stem cell studies.

For research use only. We do not sell to patients.

CAS No. : 2319882-01-2

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Stemregenin 1 hydrochloride Related Antibodies

Top Publications Citing Use of Products

    Stemregenin 1 hydrochloride purchased from MedChemExpress. Usage Cited in: Nat Commun. 2024 Jun 8;15(1):4909.  [Abstract]

    Stemregenin 1 (S: SR1; 1 μM; 3 days). WB of GLUT1 and GLUT3 expression in WCL and MEM fraction.

    Stemregenin 1 hydrochloride purchased from MedChemExpress. Usage Cited in: Nat Commun. 2024 Jun 8;15(1):4909.  [Abstract]

    Stemregenin 1 (S: SR1; 1 μM; 3 days). Operetta high content imaging analysis of 2-NBDG fluorescent tracer uptake.

    Stemregenin 1 hydrochloride purchased from MedChemExpress. Usage Cited in: RSC Adv. 2022 Apr 13;12(18):11505-11516.  [Abstract]

    Stemregenin 1 (SR1; 1 μM; 0-5 days).The absorbance at 450 nm of the CCK8 assay of the BMSCs. The number of viable BMSCs increased in all groups and there were no significant differences among the three groups on days 0, 1, 3 and 5 (p < 0.05).

    Stemregenin 1 hydrochloride purchased from MedChemExpress. Usage Cited in: RSC Adv. 2022 Apr 13;12(18):11505-11516.  [Abstract]

    Stemregenin 1 (SR1; 1 μM; 0-5 days).RT-PCR demonstrated that FICZ or SR1 prevented or exacerbated LPS-induced IL-1β, 6 and TNF-α, respectively.

    Stemregenin 1 hydrochloride purchased from MedChemExpress. Usage Cited in: Theranostics. 2021 Aug 11;11(18):8797-8812.

    N2a cells were treated with Dio (80 μM) with or without SR1 (2 μM) for 12 h. Whole cell lysates were collected and the NEP levels were determined.

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    Description

    Stemregenin 1 hydrochloride is a purine derivative that antagonizes aryl hydrocarbon receptor signaling in CD34+ cells. IC50 The value is 127 nM. Stemregenin 1 hydrochloride can be used to expand the pluripotency of hematopoietic stem cells (HSC) in stem cell studies[1].

    Molecular Weight

    466.00

    Formula

    C24H24ClN5OS
    CAS No.
    SMILES

    CC(C)N1C2=NC(C3=CSC4=C3C=CC=C4)=NC(NCCC5=CC=C(O)C=C5)=C2N=C1.Cl
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Stemregenin 1 hydrochloride Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Stemregenin 12319882-01-2SR1Stemregenin1Stemregenin-1SR 1SR-1Aryl Hydrocarbon ReceptorAhRCD34+HSCPurine derivativeInhibitorinhibitorinhibit

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