1227633-49-9
1227633-49-9
Chemical Structure
Stemregenin 1
Synonym(s): SR1
- CAS No.: 1227633-49-9
- Formula:C24H23N5OS
- Molecular Weight:429.54
IUPAC Name: 4-(2-((2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol
InChIKey: BGFHMYJZJZLMHW-UHFFFAOYSA-N
SMILES: CC(C)N1C2=NC(C3=CSC4=C3C=CC=C4)=NC(NCCC5=CC=C(O)C=C5)=C2N=C1
Biological Activity: Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with IC50 of 127 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Stemregenin 1 | 99.72% | Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with IC50 of 127 nM. | ||||||||||||||||||||
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Stemregenin 1 (GMP) | Stemregenin 1 (SR1) (GMP) is a GMP-grade Stemregenin 1 (HY-15001). GMP-grade small molecules can be used as adjuvants in cell therapy. Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with an IC50 of 127 nM. Stemregenin 1 (GMP) can competitively bind to AhR and inhibit its nuclear translocation, inhibiting osteoclastogenesis and promoting hematopoietic progenitor cell expansion by blocking the AhR-c-src-NF-κB/p-ERK MAPK-NFATc1 signaling pathway. Stemregenin 1 (GMP) can be used for the study of osteoporosis, in vitro expansion of hematopoietic stem cells, and the study of the mechanism of bone metabolic diseases. | |||||||||||||||||||||
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Stemregenin 1 (Standard) | ≥98% | Stemregenin 1 (Standard) is the analytical standard of Stemregenin 1. This product is intended for research and analytical applications. Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with IC50 of 127 nM. | ||||||||||||||||||||
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