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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
SRPK
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "SRPK" in MCE Product Catalog:
17
17 Publications Verification
Synonyms: SRPK inhibitor
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SRPIN340 is an ATP-competitive serine-arginine-rich protein kinase (SRPK) inhibitor, with a Ki of 0.89 μM for SRPK1.
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13 Cited Publications
Cat. No.: HY-117661
CAS No.: 1818389-84-2
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SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease .
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6 Cited Publications
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SRPKIN-1 is a covalent and irreversible SRPK1/2 inhibitor with IC50s of 35.6 and 98 nM, respectively. Anti-angiogenesis effect .
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1 Cited Publications
MSC-1186, a chemical probe, is a highly selective pan-SRPK inhibitor. MSC-1186 has activity for SRPK1, SRPK2 and SRPK3 with IC50 values of 2.7 nM, 81 nM and 0.6 nM, respectively. MSC-1186 can be used for the research of cancer .
Cat. No.: HY-160586
CAS No.: 2408444-93-7
Srpk1-IN-1 (compound 12) is a potent inhibitor of SRPK1, with IC50 of 0.3 nM .
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SRPIN803 is a potent CK2 and SRPK1 dual inhibitor, with IC50s of 203 nM and 2.4 μM, respectively. SRPIN803 exhibits antiangiogenic activity. SRPIN803 can be used for the research of age-related macular degeneration .
SPHINX is a selective SRPK1 inhibitor with an IC50 value of 0.58 μM. SPHINX effectively reduces Choroidal Neovascularization (CNV) in vivo. SPHINX can be used for the research of (age-related macular degenaration) AMD .
Cat. No.: HY-E70805
SRPK2 (serine-arginine protein kinase 2) is a protein kinase that is involved in cell cycle regulation and cell apoptosis. Biotin-SRPK2 Recombinant Human Active Protein Kinase is a recombinant SRPK2 protein that can be used to study SRPK2-related functions, and is biotinylated .
Cat. No.: HY-113831
CAS No.: 1005784-60-0
LK1/2-IN-3 (compound 3) is a potent and selective CLK1 and CLK2 inhibitor with IC50 values of 1.1, 2.1, 130, 260, 260 nM for CLK1, CLK2, SRPK1, SRPK2, SRPK3, respectively. CLK1/2-IN-3 shows anti-proliferative activity. CLK1/2-IN-3 reduces the levels of endogenous phosphorylated SR proteins and increases the expression of S6K mRNAs .
Cat. No.: HY-E70863
SRPK1 (serine-arginine protein kinase 1) is a protein kinase that specifically phosphorylates proteins containing serine-arginine-rich domains. SRPK1 Recombinant Human Active Protein Kinase is a recombinant SRPK1 protein that can be used to study SRPK1-related functions .
Cat. No.: HY-E70804
SRPK1 (serine-arginine protein kinase 1) is a protein kinase that specifically phosphorylates proteins containing serine-arginine-rich domains. Biotin-SRPK1 Recombinant Human Active Protein Kinase is a recombinant SRPK1 protein that can be used to study SRPK1-related functions, and is biotinylated .
Cat. No.: HY-RS13777
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SRPK1 Human Pre-designed siRNA Set A contains three designed siRNAs for SRPK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13778
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SRPK2 Human Pre-designed siRNA Set A contains three designed siRNAs for SRPK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13779
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SRPK3 Human Pre-designed siRNA Set A contains three designed siRNAs for SRPK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17173
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Srpk1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srpk1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18547
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Srpk2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srpk2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19039
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Srpk3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srpk3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25029
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Srpk2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Srpk2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-160587
CAS No.: 2095397-52-5
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Antiangiogenic agent 5 (compound 17) has anti-angiogenic activity. Antiangiogenic agent 5 show inhibition to SRPK1, with IC50 of 1.3 nM .
Cat. No.: HY-RS23623
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Srpk1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Srpk1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
